Water-Soluble Pillar[7]arene: Synthesis, pH-Controlled Complexation with Paraquat, and Application in Constructing Supramolecular Vesicles

被引：72
|
作者：
Li, Zhengtao [1 ]
Yang, Jie [1 ]
Yu, Guocan [1 ]
He, Jiuming [2 ,3 ]
Abliz, Zeper [2 ,3 ]
Huang, Feihe [1 ]
机构：
[1] Zhejiang Univ, Dept Chem, State Key Lab Chem Engn, Hangzhou 310027, Peoples R China
[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
[3] Peking Union Med Coll, Beijing 100050, Peoples R China
来源：
ORGANIC LETTERS | 2014年 / 16卷 / 07期
基金：
中国国家自然科学基金;
关键词：
HOST-GUEST COMPLEXATION; RESPONSIVE COMPLEXATION; CRYSTAL-STRUCTURES; POLYMERS; RECOGNITION; DRIVEN; NANOPARTICLES; ASSEMBLIES; RELEASE; DERIVATIVES;
D O I：
10.1021/ol500686r
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
By the introduction of 14 anionic carboxylate groups at its two rims, a water-soluble pillar[7]arene (WP7) was synthesized. Its pH-controlled complexation with paraquat G, in water was investigated. Host WP7 and guest G, formed a 1:1 [2]pseudorotaxane with a high association constant of(2.96 +/- 0.31) x 10(9) M-1 in water. Furthermore, we took advantage of this novel molecular recognition motif to fabricate a supra-amphiphile based on WP7 and an amphiphilic paraquat derivative G(2). The morphologies and sizes of self-assemblies of G(2) and WP7DG(2) were identified by transmission electron microscopy and dynamic light scattering.
引用
收藏
页码：2066 / 2069
页数：4
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