Water-Soluble Pillar[7]arene: Synthesis, pH-Controlled Complexation with Paraquat, and Application in Constructing Supramolecular Vesicles

被引：72

作者：

Li, Zhengtao ^{[1
]}

Yang, Jie ^{[1
]}

Yu, Guocan ^{[1
]}

He, Jiuming ^{[2
,3
]}

Abliz, Zeper ^{[2
,3
]}

Huang, Feihe ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, State Key Lab Chem Engn, Hangzhou 310027, Peoples R China

[2] Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China

[3] Peking Union Med Coll, Beijing 100050, Peoples R China

来源：

ORGANIC LETTERS | 2014年 / 16卷 / 07期

基金：

中国国家自然科学基金;

关键词：

HOST-GUEST COMPLEXATION; RESPONSIVE COMPLEXATION; CRYSTAL-STRUCTURES; POLYMERS; RECOGNITION; DRIVEN; NANOPARTICLES; ASSEMBLIES; RELEASE; DERIVATIVES;

D O I：

10.1021/ol500686r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

By the introduction of 14 anionic carboxylate groups at its two rims, a water-soluble pillar[7]arene (WP7) was synthesized. Its pH-controlled complexation with paraquat G, in water was investigated. Host WP7 and guest G, formed a 1:1 [2]pseudorotaxane with a high association constant of(2.96 +/- 0.31) x 10(9) M-1 in water. Furthermore, we took advantage of this novel molecular recognition motif to fabricate a supra-amphiphile based on WP7 and an amphiphilic paraquat derivative G(2). The morphologies and sizes of self-assemblies of G(2) and WP7DG(2) were identified by transmission electron microscopy and dynamic light scattering.

引用

页码：2066 / 2069

页数：4

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