Tomato products, lycopene, and prostate cancer risk

被引:45
作者
Miller, EC
Giovannucci, E
Erdman, JW
Bahnson, R
Schwartz, SJ
Clinton, SK
机构
[1] Ohio State Univ, Med Ctr, James Canc Hosp, Div Hematol & Oncol, Columbus, OH 43210 USA
[2] Ohio State Univ, Med Ctr, Solove Res Inst, Columbus, OH 43210 USA
[3] Harvard Univ, Sch Med, Channing Lab, Boston, MA 02115 USA
[4] Univ Illinois, Div Nutr Sci, Urbana, IL 61801 USA
[5] Ohio State Univ, Med Ctr, James Canc Hosp, Dept Urol, Columbus, OH 43210 USA
[6] Ohio State Univ, Dept Food Sci & Technol, Columbus, OH 43210 USA
关键词
D O I
10.1016/S0094-0143(02)00020-4
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Epidemiologic studies have suggested that men consuming tomato products have a lower risk of prostate cancer. Tomato products may contain a number of components that could influence risk. Lycopene is the carotenoid in tomato products that provides the familiar red color and has been demonstrated in laboratory studies to be a potent antioxidant. Ongoing studies will further characterize the potential benefits of tomato products or lycopene for the prevention of prostate cancer.
引用
收藏
页码:83 / +
页数:12
相关论文
共 44 条
[1]   Tomato lycopene and low density lipoprotein oxidation: A human dietary intervention study [J].
Agarwal, S ;
Rao, AV .
LIPIDS, 1998, 33 (10) :981-984
[2]  
[Anonymous], 1997, FOOD NUTR PREV CANC
[3]  
Beecher GR, 1998, P SOC EXP BIOL MED, V218, P98, DOI 10.3181/00379727-218-44282a
[4]   FRUIT, VEGETABLES, AND CANCER PREVENTION - A REVIEW OF THE EPIDEMIOLOGIC EVIDENCE [J].
BLOCK, G ;
PATTERSON, B ;
SUBAR, A .
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 1992, 18 (01) :1-29
[5]  
BOILEAU T, 2000, AM I CANC RES 10 ANN
[6]   Tissue lycopene concentrations and isomer patterns are affected by androgen status and dietary lycopene concentration in male F344 rats [J].
Boileau, TWM ;
Clinton, SK ;
Erdman, JW .
JOURNAL OF NUTRITION, 2000, 130 (06) :1613-1618
[7]   Plasma insulin-like growth factor I and prostate cancer risk: A prospective study [J].
Chan, JM ;
Stampfer, MJ ;
Giovannucci, E ;
Gann, PH ;
Ma, J ;
Wilkinson, P ;
Hennekens, CH ;
Pollak, M .
SCIENCE, 1998, 279 (5350) :563-566
[8]   Insulin like growth factor I (IGF-I), IGF-binding protein-3 and prostate cancer risk: epidemiological studies [J].
Chan, JM ;
Stampfer, MJ ;
Giovannucci, E ;
Ma, J ;
Pollak, M .
GROWTH HORMONE & IGF RESEARCH, 2000, 10 :S32-S33
[9]   Lycopene: Chemistry, biology, and implications for human health and disease [J].
Clinton, SK .
NUTRITION REVIEWS, 1998, 56 (02) :35-51
[10]  
Clinton SK, 1996, CANCER EPIDEM BIOMAR, V5, P823