Trends in the levels of N-nitrosodimethylamine in Canadian and imported beers

被引:35
作者
Sen, NP [1 ]
Seaman, SW [1 ]
Bergeron, C [1 ]
Brousseau, R [1 ]
机构
[1] HLTH PROTECT BRANCH LABS,LONGUEUIL,PQ J4K 1C1,CANADA
关键词
N-nitrosodimethylamine; NDMA; beer;
D O I
10.1021/jf9507250
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
N-Nitrosodimethylamine (NDMA) is a potent animal carcinogen that has been detected in trace levels in beers. Studies carried out by the Canadian Health Protection Branch suggest that as a result of improvement in the malt-drying techniques, NDMA levels in both Canadian and imported beers have decreased significantly over the past 10-15 years. Of 162 Canadian beers analyzed during 1982-1989, the average NDMA level was found to be 0.098 ppb (range, <0.1-0.6 ppb) as compared to average levels of 1.4 and 0.7 ppb detected in two earlier (1978 and 1980, respectively) surveys. In the two latest surveys of imported beers carried out during 1991-1992 and 1994, the respective averages were 0.71 ppb (n = 106; range, <0.1-9.1 ppb) and 0.15 ppb (n = 36; range, (0.1-3.2 ppb). The current daily intake of NDMA through beer by an average Canadian is about one-fifteenth of that estimated in 1978-1980.
引用
收藏
页码:1498 / 1501
页数:4
相关论文
共 24 条
[1]  
CUTAIA AJ, 1982, J ASSOC OFF ANA CHEM, V65, P584
[2]   N-NITROSODIMETHYLAMINE IN GERMAN BEER [J].
FROMMBERGER, R .
FOOD AND CHEMICAL TOXICOLOGY, 1989, 27 (01) :27-29
[3]   NITROSAMINES IN MALT AND MALT BEVERAGES [J].
HAVERY, DC ;
HOTCHKISS, JH ;
FAZIO, T .
JOURNAL OF FOOD SCIENCE, 1981, 46 (02) :501-505
[4]  
HOTCHKISS JH, 1989, CANCER SURV, V8, P295
[5]  
HOTCHKISS JH, 1981, J ASSOC OFF ANA CHEM, V64, P929
[6]  
*INT AG RES CANC, 1977, INT AG RES CANC, P56
[7]  
Kawabata T., 1980, IARC PUBL, V31, P481
[8]  
MANGINO MM, 1981, N NITROSO COMPOUNDS, P229
[9]   AN INVESTIGATION OF THE LEVELS OF N-NITROSODIMETHYLAMINE, APPARENT TOTAL N-NITROSO COMPOUNDS AND NITRATE IN BEER [J].
MASSEY, R ;
DENNIS, MJ ;
POINTER, M ;
KEY, PE .
FOOD ADDITIVES AND CONTAMINANTS, 1990, 7 (05) :605-615
[10]   NITROSAMINES IN BEVERAGES [J].
MCWEENY, DJ .
FOOD CHEMISTRY, 1983, 11 (04) :273-287