Near-Infrared-II Semiconducting Polymer Dots for Deep-tissue Fluorescence Imaging

被引：25

作者：

Gupta, Nidhi ^{[4
,5
]}

Chan, Yang-Hsiang ^{[1
,2
]}

Saha, Sampa ^{[3
]}

Liu, Ming-Ho ^{[6
]}

机构：

[1] Natl Chiao Tung Univ, Ctr Emergent Funct Matter Sci, Dept Appl Chem, Hsinchu 30010, Taiwan

[2] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 80708, Taiwan

[3] Indian Inst Technol Delhi, Dept Mat Sci & Engn, New Delhi 110016, India

[4] Natl Chiao Tung Univ, Dept Appl Chem, Hsinchu 30010, Taiwan

[5] Indian Inst Technol Delhi, Dept Mat Sci & Engn, New Delhi 110016, India

[6] Natl Chiao Tung Univ, Dept Appl Chem, Hsinchu 30010, Taiwan

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2021年 / 16卷 / 03期

关键词：

fluorescence; deep-tissue; NIR-II; polymer dots; optical properties; IN-VIVO; CARBON NANOTUBES; RATIONAL DESIGN; NANOPARTICLES; FLUOROPHORES; PROBES; BIODISTRIBUTION; NANOMATERIALS; CANCER; BRIGHT;

D O I：

10.1002/asia.202001348

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fluorescence imaging, particularly in the NIR-II region (1000-1700 nm), has become an unprecedented tool for deep-tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow-size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep-tissue fluorescence imaging and the facing future translation to clinical use.

引用

页码：175 / 184

页数：10

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