Efficacy of High-Dose Baclofen for Alcohol Use Disorder and Comorbid Bulimia: A Case Report

被引:6
作者
Weibel, Sebastien [1 ,2 ]
Lalanne, Laurence [1 ,2 ]
Riegert, Myriam [1 ]
Bertschy, Gilles [1 ,2 ,3 ]
机构
[1] Strasbourg Univ Hosp, Dept Psychiat & Mental Hlth, F-67091 Strasbourg, France
[2] INSERM, Unit 1114, Strasbourg, France
[3] Strasbourg Univ, Sch Med, Translat Med Federat, Strasbourg, France
关键词
addiction; craving; baclofen; bulimia; alcohol; drug;
D O I
10.1080/15504263.2015.1104483
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
High-dose baclofen is a promising treatment for alcohol use disorder, with a specific action on craving. A more general action on craving in other addictive disorders has been suggested based on the hypothesis of a common neurobiological pathway in addictions. We report the case of a woman with both alcohol use disorder and bulimia nervosa. There was a positive response to high-dose baclofen on alcohol craving, but no response on food craving. The case illustrates that craving could be differentially responsive to anti-craving drugs.
引用
收藏
页码:203 / 204
页数:2
相关论文
共 4 条
[1]   World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Pharmacological Treatment of Eating Disorders [J].
Aigner, Martin ;
Treasure, Janet ;
Kaye, Walter ;
Kasper, Siegfried .
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 2011, 12 (06) :400-443
[2]   Clinical Experience with Baclofen in the Management of Alcohol-Dependent Patients with Psychiatric Comorbidity: A Selected Case Series [J].
Dore, G. M. ;
Lo, K. ;
Juckes, L. ;
Bezyan, S. ;
Latt, N. .
ALCOHOL AND ALCOHOLISM, 2011, 46 (06) :714-720
[3]   Addicted to palatable foods: comparing the neurobiology of Bulimia Nervosa to that of drug addiction [J].
Hadad, Natalie A. ;
Knackstedt, Lori A. .
PSYCHOPHARMACOLOGY, 2014, 231 (09) :1897-1912
[4]   Abstinence and 'Low-Risk' Consumption 1 Year after the Initiation of High-Dose Baclofen: A Retrospective Study among 'High-Risk' Drinkers [J].
Rigal, Laurent ;
Alexandre-Dubroeucq, Constance ;
de Beaurepaire, Renaud ;
Le Jeunne, Claire ;
Jaury, Philippe .
ALCOHOL AND ALCOHOLISM, 2012, 47 (04) :439-442