Adult Intestinal Transplantation

被引：43

作者：

Matsumoto, Cal S. ^{[1
]}

Subramanian, Sukanya ^{[1
]}

Fishbein, Thomas M. ^{[1
]}

机构：

[1] Medstar Georgetown Univ Hosp, Medstar Georgetown Transplant Inst, 3800 Reservoir Rd Northwest,2 PHC Bldg, Washington, DC 20007 USA

来源：

GASTROENTEROLOGY CLINICS OF NORTH AMERICA | 2018年 / 47卷 / 02期

关键词：

Adult intestinal transplantation; Intestinal transplant indications; Intestinal transplant outcome; Virtual crossmatch; GASTRIC BYPASS; CROHNS-DISEASE; TRENDS; LIVER;

D O I：

10.1016/j.gtc.2018.01.011

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Adult intestinal transplant differs significantly from pediatric intestinal transplant. Although indications have remained largely consistent since 2000, indications for adults have expanded over the last 2 decades to include motility disorders and desmoid tumors. Graft type in adult recipients depends on the distinct anatomic characteristics of the adult recipient. Colonic inclusion, although initially speculated to portend unfavorable outcomes due to complex host-bacterial interactions, has increased over the past 2 decades with superior graft survival and improved patient quality of life. Overall, outcomes have steadily improved. For adult intestinal transplant candidates, intestinal transplantation remains a mainstay therapy for complicated intestinal failure and is a promising option for other life-threatening and debilitating conditions.

引用

页码：341 / +

页数：16

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