Anticancer activity of organotin(IV) carboxylates

被引：108
作者：
Amir, Muhammad Kashif [1 ]
Khan, Shahanzeb [1 ,2 ]
Zia-ur-Rehman [1 ]
Shah, Afzal [1 ]
Butler, Ian S. [3 ]
机构：
[1] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan
[2] Univ Sci & Technol Bannu, Dept Chem, KPK, Pakistan
[3] McGill Univ, Dept Chem, Montreal, PQ H3A 2K6, Canada
来源：
INORGANICA CHIMICA ACTA | 2014年 / 423卷
关键词：
Metallodrugs; Cancer; Organotin(IV) carboxylates; Antitumor activity; VITRO ANTITUMOR-ACTIVITY; IN-VITRO; STRUCTURAL-CHARACTERIZATION; CRYSTAL-STRUCTURES; SPECTROSCOPIC CHARACTERIZATION; DIORGANOTIN(IV) DERIVATIVES; BIOLOGICAL-ACTIVITY; OROTIC-ACID; CELL-LINES; COMPLEXES;
D O I：
10.1016/j.ica.2014.07.053
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
This article provides a critical review of the anticancer activity of organotin(IV) carboxylates in the last five years. Most of the organotin(IV) carboxylates discussed in this review have greater anticancer activity against different cell lines than do the standard drugs. Moreover, some of these organotin(IV) carboxylates have pronounced anticancer activity even against cisplatin-resistive cancer cells. The review also highlights structure-activity relationships. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：14 / 25
页数：12
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