Model-Based Approach to the Localization of Infarction

被引:12
作者
Farina, D. [1 ]
Doessel, O. [1 ]
机构
[1] Univ Karlsruhe, Inst Biomed Techn, Kaiserstr 12, D-76131 Karlsruhe, Germany
来源
COMPUTERS IN CARDIOLOGY 2007, VOL 34 | 2007年 / 34卷
关键词
D O I
10.1109/CIC.2007.4745449
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A model-based approach to noninvasively determine the location and size of the infarction scar is proposed, that in addition helps to estimate the risk of arrhythmias. The approach is based on the optimization of an electrophysiological heart model with an introduced infarction scar to fit the multichannel ECG measured on the surface of the patient's thorax. This model delivers the distributions of transmembrane voltages (TMV) within the ventricles during a single heart cycle. The forward problem of electrocardiography is solved in order to obtain the simulated ECG of the patient. This ECG is compared with the measured one, the difference is used as the criterion for optimization of model parameters, which include the site and size of infarction scar.
引用
收藏
页码:173 / +
页数:2
相关论文
共 8 条
[1]   MYOCARDIAL ELECTRICAL-IMPEDANCE MAPPING OF ISCHEMIC SHEEP HEARTS AND HEALING ANEURYSMS [J].
FALLERT, MA ;
MIROTZNIK, MS ;
DOWNING, SW ;
SAVAGE, EB ;
FOSTER, KR ;
JOSEPHSON, ME ;
BOGEN, DK .
CIRCULATION, 1993, 87 (01) :199-207
[2]  
Farina D, 2005, COMPUT CARDIOL, V32, P571
[3]   The dielectric properties of biological tissues .2. Measurements in the frequency range 10 Hz to 20 GHz [J].
Gabriel, S ;
Lau, RW ;
Gabriel, C .
PHYSICS IN MEDICINE AND BIOLOGY, 1996, 41 (11) :2251-2269
[4]  
GLAS M, 1996, THESIS U KARLSRUHE T
[5]  
*PHYSIONET, COMP CARD CHALL 2007
[6]  
PODRID PJ, 1997, POSTGR MED, V102
[7]   A model for human ventricular tissue [J].
ten Tusscher, KHWJ ;
Noble, D ;
Noble, PJ ;
Panfilov, AV .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2004, 286 (04) :H1573-H1589
[8]   The use of the spatial covariance in computing pericardial potentials [J].
van Oosterom, A .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1999, 46 (07) :778-787