Oil droplet generation in PDMS microchannel using an amphiphilic continuous phase

被引：17

作者：

Chae, Su-Kyoung ^{[1
,2
]}

Lee, Chang-Ha ^{[2
]}

Lee, Soo Hyun ^{[1
]}

Kim, Tae-Song ^{[1
]}

Kang, Ji Yoon ^{[1
]}

机构：

[1] Korea Inst Sci & Technol, Nanobiores Ctr, Seoul 136791, South Korea

[2] Yonsei Univ, Dept Chem Engn, Seoul 120749, South Korea

来源：

LAB ON A CHIP | 2009年 / 9卷 / 13期

关键词：

POLYDIMETHYLSILOXANE; RECOVERY; SURFACES; TENSION;

D O I：

10.1039/b816756g

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This paper reports an amphiphilic solution can be used as a new continuous phase to generate double droplet emulsions (water/oil/IPA) with neither surface treatment nor surfactant in PDMS microfluidic chip. The affinity of various amphiphilic solutions in the microchannel was influenced by the polarity ratio and the size of molecules. The polarity ratio of isopropyl alcohol (IPA) was closest to that of the recovered PDMS surface and the chain length of IPA was also suitable for high affinity. IPA showed the highest affinity for the recovered PDMS and was selected as the continuous phase to form oil droplets in a PDMS microchannel. With this new continuous phase solution, IPA, we could successfully generate not only oil droplets but also double emulsions in the PDMS microfluidic chips.

引用

页码：1957 / 1961

页数：5

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