Metal-Free Three-Component Coupling Reaction of Ketones with Electron-rich Arenes and Selenium Dioxide for the Synthesis of α-Arylselanyl Ketones

被引：7

作者：

Wanniang, Kmendashisha ^{[1
]}

Shangpliang, O. Risuklang ^{[1
]}

Marpna, Ibakyntiew D. ^{[1
]}

Lipon, Tyrchain Mitre ^{[1
]}

Laloo, Badaker M. ^{[1
]}

Myrboh, Bekington ^{[1
]}

机构：

[1] North Eastern Hill Univ, Ctr Adv Studies Chem, Dept Chem, Shillong 793022, Meghalaya, India

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2020年 / 85卷 / 23期

关键词：

ORGANOSELENIUM CHEMISTRY; CARBONYL-COMPOUNDS; ALLYLIC SELENIDES; ALDEHYDES; PROTOCOL; REAGENT; AMINES; SELENOKETONES; SELENYLATION; CONVERSION;

D O I：

10.1021/acs.joc.0c02028

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A metal-free three-component coupling reaction of aryl alkyl/alkyl ketones, SeO2, and phenols/anisoles is described. This multicomponent reaction provides a straightforward and facile pathway for the synthesis of alpha-((4-hydroxy/methoxyphenyl)selanyl)-aryl alkyl/alkyl ketones in the presence of p-toluenesulfonic acid for the C-Se bond formation process. The method offers an attractive and simple procedure using commonly available shelf reagents to deliver organo-selenides that, to our knowledge, are being reported here for the first time.

引用

页码：15652 / 15659

页数：8

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