Fluorimetric Properties of 3-Aminoflavone Biomolecule (3-AF). X-ray Crystal Structure of New Polymorph of 3-AF

被引：5

作者：

Pajak, Wojciech ^{[1
]}

Fabijanska, Malgorzata ^{[2
]}

Wojciechowski, Jakub ^{[3
]}

Wolf, Wojciech M. ^{[3
]}

Kilanowicz, Anna ^{[4
]}

Brzezinska, Elzbieta ^{[1
]}

Ochocki, Justyn ^{[2
]}

机构：

[1] Med Univ Lodz, Dept Analyt Chem, 1 Muszynskiego Str, PL-90151 Lodz, Poland

[2] Med Univ Lodz, Dept Bioinorgan Chem, 1 Muszynskiego Str, PL-90151 Lodz, Poland

[3] Lodz Univ Technol, Inst Gen & Ecol Chem, 116 Zeromskiego St, PL-90924 Lodz, Poland

[4] Med Univ Lodz, Dept Toxicol, 1 Muszynskiego Str, PL-90151 Lodz, Poland

来源：

MOLECULES | 2019年 / 24卷 / 16期

关键词：

3-aminoflavone; X-ray crystallography; fluorescence; LOD (limit of detection); LOQ (limit of quantification); concentration quenching; FLAVONOIDS; FLUORESCENCE; MECHANISMS;

D O I：

10.3390/molecules24162927

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The crystal structure of the new polymorphic form of 3-aminoflavone (3-AF) has been determined by single crystal X-ray diffraction. This report presents results of fluorimetric studies on 3-AF in methanol and aquatic solvents. Based on 3D fluorescence emission spectra, optimal values for excitation (lambda(ex)) and emission/analytical (lambda(em)) wavelength, the analytical concentration range as well as the range of concentration quenching for the studied compound were established. Moreover, the limit of detection (LOD) and the limit of quantification (LOQ) were determined. The results were compared with those obtained using the standard UV-Vis absorption spectrophotometric method. The effect of acidity (pH) and the concentration of halide anions (chlorides, bromides, iodides and fluorides) on fluorescence quenching were analysed.

引用

页数：15

共 28 条

[21] Synthesis, single-crystal and solution structure analysis and in vitro cytotoxic activity of two novel complexes of ruthenium(II) with in situ formed flavanone-based ligands. [J].

Ochocki, Justyn ;

Kasprzak, Maria ;

Checinska, Lilianna ;

Erxleben, Andrea ;

Zyner, Elzbieta ;

Szmigiero, Leszek ;

Garza-Ortiz, Ariadna ;

Reedijk, Jan .

DALTON TRANSACTIONS, 2010, 39 (40) :9711-9718

[22] The immunomodulatory role of plant polyphenols [J].

Paszkiewicz, Malgorzata ;

Budzynska, Aleksandra ;

Rozalska, Barbara ;

Sadowska, Beata .

POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ, 2012, 66 :637-646

[23] Flavonoids as Analytical Reagents [J].

Pyrzynska, Krystyna ;

Pekal, Anna .

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, 2011, 41 (04) :335-345

[24] Hirshfeld surface analysis [J].

Spackman, Mark A. ;

Jayatilaka, Dylan .

CRYSTENGCOMM, 2009, 11 (01) :19-32

[25] Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance [J].

Stone, M. Rhia L. ;

Butler, Mark S. ;

Phetsang, Wanida ;

Cooper, Matthew A. ;

Blaskovich, Mark A. T. .

TRENDS IN BIOTECHNOLOGY, 2018, 36 (05) :523-536

[26] Effect of solvent polarity on photophysical parameters of 3-aminoflavone [J].

Wisniewski, Lukasz ;

Deperasinska, Irena ;

Zurowska, Boguslawa ;

Szemik-Hojniak, Anna .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2011, 224 (01) :62-67

[27] Current status of platinum-based antitumor drugs [J].

Wong, E ;

Giandomenico, CM .

CHEMICAL REVIEWS, 1999, 99 (09) :2451-2466

[28] Synthesis, spectroscopy and magnetism of novel metal complexes of 3-aminoflavone (3-af). X-ray crystal structure of 3-af and [Cu(3-af)2(NO3)2] [J].

Zurowska, Bogumila ;

Erxleben, Andrea ;

Glinka, Lukasz ;

Leczycka, Malgorzata ;

Zyner, Elzbieta ;

Ochocki, Justyn .

INORGANICA CHIMICA ACTA, 2009, 362 (03) :739-744

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