Determination of six lignans in Schisandra chinensis (Turcz.) Baill. Fruits and related Chinese multiherb remedies by HPLC

被引：50
|
作者：
Zhang, Hai [2 ]
Zhang, Guoqing [2 ]
Zhu, Zhenyu [1 ]
Zhao, Liang [2 ]
Fei, Yang [2 ]
Jing, Jing [1 ]
Chai, Yifeng [1 ]
机构：
[1] Second Mil Med Univ, Sch Pharm, Shanghai 200433, Peoples R China
[2] Eastern Hepatobiliary Surg Hosp, Dept Pharm, Shanghai 200438, Peoples R China
来源：
FOOD CHEMISTRY | 2009年 / 115卷 / 02期
关键词：
Schisandra chinensis; Lignans; High-performance liquid chromatography; CAPILLARY ELECTROCHROMATOGRAPHY; LIQUID-CHROMATOGRAPHY; MASS-SPECTROMETRY; CONSTITUENTS; MEDICINES;
D O I：
10.1016/j.foodchem.2008.12.010
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A simple, rapid and specific HPLC method was established for simultaneous determination of six major lignans in Schisandra chinensis and related Chinese multiherb remedies (CMRs) containing this herb. The six lignans were successfully separated on a C-18 column by gradient elution using acetonitrile and water as the mobile phase, and detection wavelength was set at 225 rim. The method was validated through the following performance criteria: linearity, precision, repeatability, stability, accuracy, limit of detection (LOD) and quantification (LOQ). This assay was successfully used for determination of six lignans in 10 raw herbs collected from different regions in China and five Chinese multiherb remedies. Significant variations were demonstrated in the contents of six compounds in these samples. This HPLC method established is suitable for routine quantitative analysis of S. chinensis and multiherb remedies containing this herb. Crown Copyright (C) 2008 Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：735 / 739
页数：5
相关论文
共 50 条
  • [31] Four sesquiterpenoids from the vegetable raw material Schisandra chinensis (Turcz.) Baill.: leaves and stems
    Yang, Yong-Cheng
    Liu, Lu-Qi
    Wang, Kun-Jun
    Zhang, Xue-Qing
    Fan, San-Peng
    Gao, Xiao-Xu
    Wang, An-Hua
    Jia, Jing-Ming
    Fu, Chun-Wang
    NATURAL PRODUCT RESEARCH, 2022, 36 (21) : 5429 - 5437
  • [32] IN VITRO PROTECTIVE EFFECTS OF SCHISANDRA CHINENSIS (TURCZ.) BAILL. ACTIVE COMPOUNDS TOWARDS CISPLATIN TUBULOTOXICITY
    Bunel, V
    Antoine, M-H
    Nortier, J.
    Duez, P.
    Stevigny, C.
    ACTA CLINICA BELGICA, 2013, 68 (04): : 317 - 317
  • [33] Analysis of volatile fractions of Schisandra chinensis (Turcz.) baill. using GC-MS and chemometric resolution
    Li, XN
    Cui, H
    Song, YQ
    Liang, YZ
    Chau, FT
    PHYTOCHEMICAL ANALYSIS, 2003, 14 (01) : 23 - 33
  • [34] Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives
    Nowak, Adriana
    Zaklos-Szyda, Malgorzata
    Blasiak, Janusz
    Nowak, Agnieszka
    Zhang, Zhuo
    Zhang, Bolin
    NUTRIENTS, 2019, 11 (02)
  • [35] Accumulation of dibenzocyclooctadiene lignans in agar cultures and in stationary and agitated liquid cultures of Schisandra chinensis (Turcz.) Baill
    Agnieszka Szopa
    Adam Kokotkiewicz
    Urszula Marzec-Wróblewska
    Adam Bucinski
    Maria Luczkiewicz
    Halina Ekiert
    Applied Microbiology and Biotechnology, 2016, 100 : 3965 - 3977
  • [36] Accumulation of dibenzocyclooctadiene lignans in agar cultures and in stationary and agitated liquid cultures of Schisandra chinensis (Turcz.) Baill
    Szopa, Agnieszka
    Kokotkiewicz, Adam
    Marzec-Wroblewska, Urszula
    Bucinski, Adam
    Luczkiewicz, Maria
    Ekiert, Halina
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2016, 100 (09) : 3965 - 3977
  • [37] Bioreactor type affects the accumulation of phenolic acids and flavonoids in microshoot cultures of Schisandra chinensis (Turcz.) Baill.
    Szopa, Agnieszka
    Kokotkiewicz, Adam
    Bednarz, Marcelina
    Jafernik, Karolina
    Luczkiewicz, Maria
    Ekiert, Halina
    PLANT CELL TISSUE AND ORGAN CULTURE, 2019, 139 (01) : 199 - 206
  • [38] Bioreactor type affects the accumulation of phenolic acids and flavonoids in microshoot cultures of Schisandra chinensis (Turcz.) Baill.
    Agnieszka Szopa
    Adam Kokotkiewicz
    Marcelina Bednarz
    Karolina Jafernik
    Maria Luczkiewicz
    Halina Ekiert
    Plant Cell, Tissue and Organ Culture (PCTOC), 2019, 139 : 199 - 206
  • [39] Production of deoxyschizandrin and γ-schizandrin in shoot-differentiating and undifferentiating callus cultures of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine)
    Szopa, Agnieszka
    Ekiert, Halina
    JOURNAL OF BIOTECHNOLOGY, 2013, 165 (3-4) : 209 - 213
  • [40] Hepatoprotective effect of Schisandra chinensis (Turcz.) Baill. lignans and its formula with Rubus idaeus on chronic alcohol-induced liver injury in mice
    Wang, Ou
    Cheng, Qian
    Liu, Jia
    Wang, Yong
    Zhao, Liang
    Zhou, Feng
    Ji, Baoping
    FOOD & FUNCTION, 2014, 5 (11) : 3018 - 3025
12345