Reduction in Mean Deviation Values in Automated Perimetry in Eyes With Multifocal Compared to Monofocal Intraocular Lens Implants

PURPOSE: To evaluate differences in mean deviation values in automated perimetry in healthy eyes with multifocal compared to monofocal intraocular lens (IOL) implants. DESIGN: Prospective, age-matched, comparative analysis. METHODS: SETTING: Single-center, tertiary referral academic practice. PATIENT POPULATION: A total of 37 healthy eyes in 37 patients with bilateral multifocal (n = 22) or monofocal (n = 15) IOL implants were studied. INTERVENTION/OBSERVATION PROCEDURE: Humphrey Visual Field 10-2 testing was performed on all patients. MAIN OUTCOME MEASURES: Mean deviation (MD) and pattern standard deviation (PSD) numerical values were evaluated and compared between groups. RESULTS: The average MD was -2.84 dB (SD 2.32) for the multifocal IOL group and -0.97 dB (SD 1.58) for the monofocal IOL group (P = .006). There was no significant difference in PSD between the 2 groups (P = .99). Eyes that had the visual field 10-2 testing >= 6 months from time of IOL placement showed no improvement in MD when compared to eyes that were tested within 6 months from IOL placement. CONCLUSION: Multifocal IOL implants cause significant nonspecific reduction in MD values on Humphrey Visual Field 10-2 testing that does not improve with time or neuroadaptation. Multifocal IOL implants may be inadvisable in patients where central visual field reduction may not be tolerated; such as macular degeneration, retinal pigment epithelium changes, and glaucoma. (C) 2014 by Elsevier Inc. All rights reserved.