Sentinel lymph node biopsy for cutaneous melanoma: A propos of 144 cases

被引：0
作者：
Konofaos, Petros [1 ]
Karypidis, Dimitrios [2 ]
Chrisostomidis, Chrisostomos [2 ]
Kostopoulos, Epaminondas [2 ]
Champsas, Gregorios [2 ]
Papadopoulos, Othon [1 ,2 ]
机构：
[1] Univ Athens, Laiko Gen Hosp, Dept Propedeut Surg 2, Athens, Greece
[2] A Sygros Hosp, Dept Plast & Reconstruct Surg, Athens, Greece
来源：
JOURNAL OF BUON | 2014年 / 19卷 / 01期
关键词：
melanoma; predisposition to sentinel lymph node positivity; recurrence; sentinel lymph node biopsy; survival; AMERICAN JOINT COMMITTEE; PROGNOSTIC FACTORS ANALYSIS; TERM-FOLLOW-UP; MALIGNANT-MELANOMA; STAGE-I; METASTATIC MELANOMA; BASIN DISEASE; MITOTIC RATE; RECURRENCE; POSITIVITY;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose: The aim of this study was to identify the predictive factors of a positive sentinel lymph node (SLN) in patients with cutaneous malignant melanomas and tumor progression. Methods: From October of 2000 to January of 2006, 144 patients with cutaneous malignant melanoma underwent SLN biopsy. Patients were divided into two groups according to the SLN status (positive vs negative) which were compared with regards to patient demographics and primary tumor characteristics. Results: In 37 (25.69%) patients SLN biopsy was positive. Nodular melanomas (p=0.047), blood (p=0.010) and lymph (p<0.001) vessel infiltration, mitotic rate (p=0.019) and Breslow thickness (p=0.012) were predictive of a positive SLN biopsy. The overall recurrence, mortality and the overall disease free survival (DFS) rates were 6.25, 1.4 and 93.75, respectively. Conclusion: SLN biopsy is the most important predictor of early disease recurrence and survival in patients with cutaneous malignant melanoma. Considering all the examined factors, a positive SLN biopsy is related with Breslow thickness and lymph vessel infiltration.
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收藏
页码：263 / 272
页数：10
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