Delirium is a risk factor for institutionalization and functional decline in older hip fracture patients

被引:64
作者
Krogseth, Maria [1 ,2 ]
Wyller, Torgeir Bruun [1 ,2 ]
Engedal, Knut [2 ,3 ]
Juliebo, Vibeke [1 ,4 ]
机构
[1] Oslo Univ Hosp, Dept Geriatr Med, N-0424 Oslo, Norway
[2] Univ Oslo, Inst Clin Med, N-0316 Oslo, Norway
[3] Oslo Univ Hosp, Norwegian Ctr Ageing & Hlth, N-0424 Oslo, Norway
[4] Oslo Univ Hosp, Dept Cardiol, N-0424 Oslo, Norway
关键词
Delirium; Elderly; Functional decline; Institutionalization; Hip fracture; POSTOPERATIVE DELIRIUM; INFORMANT QUESTIONNAIRE; COGNITIVE DECLINE; ELDERLY-PATIENTS; MORTALITY; OUTCOMES; VALIDATION; PREDICTOR; PROGNOSIS; RECOVERY;
D O I
10.1016/j.jpsychores.2013.10.006
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objectives: The risk of institutionalization and functional decline is substantial after a hip fracture. However, previous research has not established the extent to which delirium plays a contributory role. Methods: Using a prospective design, we studied 207 hip fracture patients aged 65 and older, home-dwelling before the fracture. Patients were screened daily for delirium using the Confusion Assessment Method. Proxy information on pre-fracture cognitive function and function in activities of daily living (ADL) was obtained using the Informant Questionnaire on Cognitive Decline in the Elderly, 16-item version, and the Barthel ADL Index. After 6 months, the patients' functions in ADL measured by the Barthel ADL Index and place of living were registered. Results: Delirium was present in 80 patients (39%) during the hospital stay. After 6 months, 33 (16%) were institutionalized. Delirium and lower Barthel ADL Index score were the main risk factors for institutionalization with an adjusted odds ratio (AOR) of 5.50 (95% Cl = 1.77-17.11) and 0.54(95% Cl = 0.40-0.74) respectively. In patients able to return to their private home, the independent risk factors for functional decline were higher age (B = 0.053,95% Cl = 0.003-0.102) and delirium (B = 0.768,95% Cl = 0.039-1.497). Conclusions: At 6 month follow-up, delirium constitutes an independent risk factor for institutionalization and functional decline in hip fracture patients living at home prior to the fracture. (C) 2013 Elsevier Inc All rights reserved.
引用
收藏
页码:68 / 74
页数:7
相关论文
共 46 条
[1]  
[Anonymous], 1968, NUTR AN
[2]  
[Anonymous], 2000, DIAGN STAT MAN MENT, DOI DOI 10.1176/APPI.BOOKS.9780890425787
[3]   High risk of cognitive and functional decline after postoperative delirium -: A three-year prospective study [J].
Bickel, Horst ;
Gradinger, Reiner ;
Kochs, Eberhard ;
Foerst, Hans .
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2008, 26 (01) :26-31
[4]   The Memorial Delirium Assessment Scale [J].
Breitbart, W ;
Rosenfeld, B ;
Roth, A ;
Smith, MJ ;
Cohen, K ;
Passik, S .
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 1997, 13 (03) :128-137
[5]   The incidence of delirium associated with orthopedic surgery: a meta-analytic review [J].
Bruce, Angela J. ;
Ritchie, Craig W. ;
Blizard, Robert ;
Lai, Rosalind ;
Raven, Peter .
INTERNATIONAL PSYCHOGERIATRICS, 2007, 19 (02) :197-214
[6]   A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION [J].
CHARLSON, ME ;
POMPEI, P ;
ALES, KL ;
MACKENZIE, CR .
JOURNAL OF CHRONIC DISEASES, 1987, 40 (05) :373-383
[7]  
Collin C, 1988, Int Disabil Stud, V10, P61
[8]   Epidemiology and outcomes of osteoporotic fractures [J].
Cummings, SR ;
Melton, LJ .
LANCET, 2002, 359 (9319) :1761-1767
[9]   Delirium on hospital admission in aged hip fracture patients: Prediction of mortality and 2-year functional outcomes [J].
Dolan, MM ;
Hawkes, WG ;
Zimmerman, SI ;
Morrison, RS ;
Gruber-Baldini, AL ;
Hebel, JR ;
Magaziner, J .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2000, 55 (09) :M527-M534
[10]   Review: A gentle introduction to imputation of missing values [J].
Donders, A. Rogier T. ;
van der Heijden, Geert J. M. G. ;
Stijnen, Theo ;
Moons, Karel G. M. .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2006, 59 (10) :1087-1091