Synthesis of GO-Fe3O4-PANI nanocomposite with excellent NIR absorption property

被引:30
|
作者
Soysal, Furkan [1 ,2 ]
Ciplak, Zafer [1 ]
Getiren, Bengu [1 ]
Gokalp, Ceren [1 ]
Yildiz, Nuray [1 ]
机构
[1] Ankara Univ, Dept Chem Engn, TR-06100 Ankara, Turkey
[2] Yildirim Beyazit Univ, Dept Chem Engn, TR-06010 Ankara, Turkey
关键词
Photothermal therapy; Graphene; Superparamagnetic iron oxide; Polyaniline; Conversion efficiency; NEAR-INFRARED LIGHT; PHOTOTHERMAL THERAPY; POLYANILINE NANOPARTICLES; IRON-OXIDE; POLYPYRROLE NANOPARTICLES; AU NANOPARTICLES; GRAPHENE OXIDE; CANCER-THERAPY; DRUG CARRIER; FABRICATION;
D O I
10.1016/j.colsurfa.2019.123623
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Photothermal therapy is considered as an alternative to conventional cancer therapy methods, which is a mild practice compared to chemotherapy, radiotherapy, and surgery. The purpose of this study is to synthesize a photosensitizing agent having strong near-infrared (NIR) ((similar to)808 nm) absorption, low cytotoxicity, magnetic properties, and excellent stability. For this purpose, graphene oxide-iron (II, III) oxide-polyaniline (GO-Fe3O4-PANI) was synthesized for the first time towards photothermal application and characterized by UV-vis, FTIR, XRD, TEM, and VSM analyses. The photothermal performance of the nanocomposite was investigated at various concentrations (0.1, 0.05, 0.025 mg/mL) under 1, 1.5, and 2.5 W/cm(2) laser power density values. Photothermal conversion efficiency values of the samples were calculated by time constant method and a maximum of 65.80% efficiency was obtained (0.1 g/mL concentration at 1.5 W/cm(2) for 5 min). This novel nanocomposite demonstrated superior results among PANI based photosensitizing agents.
引用
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页数:8
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