The influence of the instabilities in modelling arteriovenous junction haemodynamics

被引:7
作者
Broderick, Stephen P. [1 ,2 ]
Houston, J. Graeme [3 ]
Walsh, Michael T. [1 ,2 ]
机构
[1] Univ Limerick, Dept Mech Aeronaut & Biomed Engn, Ctr Appl Biomed Engn Res, Limerick, Ireland
[2] Univ Limerick, Mat Surface Sci Inst, Limerick, Ireland
[3] Univ Dundee, Ninewells Hosp & Med Sch, Cardiovasc & Diabet Med, Dundee DD1 9SY, Scotland
关键词
Computational fluid dynamics; Arteriovenous junction; Wall shear stress; Turbulence; Instabilities; Large eddy simulation; DIRECT NUMERICAL-SIMULATION; WALL SHEAR-STRESS; TRANSITIONAL FLOW; STENOTIC FLOWS; HEMODIALYSIS; GRAFT; VEIN; TURBULENCE; VELOCITY; FISTULAS;
D O I
10.1016/j.jbiomech.2015.07.038
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The arteriovenous junction is characterised by high flow rates, large pressure difference and typically a palpable thrill or audible bruit, associated with turbulent flow. However, the arteriovenous junction is frequently studied with the assumption of streamline flow. This assumption is based on the Reynolds number calculation, although other factors can contribute to turbulent generation. In this study, the presence of instabilities is examined and the influencing factors discussed. This was performed using a pseudo-realistic geometry with adapted graft angles, vein diameter, outflow split ratio and graft inlet velocity values. Correlation was performed between steady and unsteady averaged simulation cases with correlation performance ranked. Overall the arteriovenous junction is capable of possessing highly disturbed flows, in which strict modelling requirements are necessary to capture such instabilities and avoid erroneous conclusions. Vein diameter and flow split ratio contribute to turbulent generation, thus Reynolds number cannot be used as a sole turbulent criterion in the arteriovenous junction. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:3591 / 3598
页数:8
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