Sleep disturbances in obsessive-compulsive disorder: influence of depression symptoms and trait anxiety

被引：25

作者：

Segalas, Cinto ^{[1
,2
,3
]}

Labad, Javier ^{[2
,4
]}

Salvat-Pujol, Neus ^{[1
,2
,3
,4
]}

Real, Eva ^{[1
,2
]}

Alonso, Pino ^{[1
,2
,3
]}

Bertolin, Sara ^{[1
]}

Jimenez-Murcia, Susana ^{[1
,3
,5
]}

Soriano-Mas, Carles ^{[1
,2
,6
]}

Monasterio, Carmen ^{[7
,8
]}

Menchon, Jose M. ^{[1
,2
,3
]}

Soria, Virginia ^{[1
,2
,3
]}

机构：

[1] Bellvitge Univ Hospital, Bellvitge Biomed Res Inst IDIBELL, Neurosci Grp Psychiat & Mental Hlth, Dept Psychiat, Feixa Llarga S-N, Barcelona 08907, Spain

[2] Carlos III Hlth Inst, Ctr Invest Biomed Red Salud Mental CIBERSAM, Madrid, Spain

[3] Univ Barcelona, Sch Med, Dept Clin Sci, Barcelona, Spain

[4] Inst Invest & Innovacio Parc Tauli I3PT, Dept Mental Hlth, Consorci Sanitari Maresme, Barcelona, Spain

[5] Carlos III Hlth Inst, Ctr Invest Biomed Red Fisiopatol Obesidad & Nutr, Madrid, Spain

[6] Univ Autonoma Barcelona, Dept Psychobiol & Methodol Hlth Sci, Bellaterra, Spain

[7] Bellvitge Univ Hospital, Bellvitge Biomed Res Inst IDIBELL, Sect Resp Med, Multidisciplinary Sleep Unit,Dept Resp Med, Barcelona, Spain

[8] Carlos III Hlth Inst, Ctr Invest Biomed Red Enfermedades Resp CIBERES, Madrid, Spain

来源：

BMC PSYCHIATRY | 2021年 / 21卷 / 01期

关键词：

Obsessive-compulsive disorder; Sleep disorders; Sleep quality; Delayed sleep phase disorder; Depression; Trait anxiety; CIRCADIAN-RHYTHMS; REM-SLEEP; INSOMNIA; STATE; PHASE; QUALITY; HEALTH;

D O I：

10.1186/s12888-021-03038-z

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Background Sleep disturbances have been reported in obsessive-compulsive disorder (OCD) patients, with heterogeneous results. The aim of our study was to assess sleep function in OCD and to investigate the relationship between sleep and the severity of obsessive-compulsive (OC) symptoms, depressive symptoms and trait anxiety. Methods Sleep quality was measured in 61 OCD patients and 100 healthy controls (HCs) using the Pittsburgh Sleep Quality Index (PSQI). Multiple linear regression was conducted to explore the association between sleep and psychopathological measures; a mediation analysis was also performed. Results OCD patients showed poor sleep quality and more sleep disturbances compared to HCs. The severity of depression, trait anxiety and OC symptomatology were correlated with poor sleep quality. Multiple linear regression analyses controlling for potential confounders revealed that the severity of depression and trait anxiety were independently related to poor sleep quality in OCD. A mediation analysis showed that both the severity of trait anxiety and depression mediate the relationship between the severity of OC symptoms and poor sleep quality among patients with OCD. Conclusions Our findings support the existence of sleep disturbances in OCD. Trait anxiety and depression play a key role in sleep quality among OCD patients.

引用

页数：10

共 42 条

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