Course of Sars-CoV2 Infection in Patients with Cancer Treated with anti-PD-1: A Case Presentation and Review of the Literature

被引:10
作者
Pala, Laura [1 ]
Conforti, Fabio [1 ]
Cocorocchio, Emilia [1 ]
Ferrucci, Pierfrancesco [1 ]
De Pas, Martino Tommaso [1 ]
Stucchi, Sara [1 ,2 ]
Repetto, Matteo [3 ,4 ]
Saponara, Maristella [1 ]
Queirolo, Paola [1 ]
机构
[1] European Inst Oncol IRCCS, Div Med Oncol Melanoma Sarcoma & Rare Tumors, IEO, Via Ripamonti 435, I-20141 Milan, Italy
[2] European Inst Oncol IRCCS, IEO, Res Nurses Team, Milan, Italy
[3] European Inst Oncol IRCCS, Div Early Drug Dev Innovat Therapy, IEO, Milan, Italy
[4] Univ Milan, Dept Oncol & Haematol, Milan, Italy
关键词
Melanoma; cancer; COVID-19; anti-PD-1; COVID-19;
D O I
10.1080/07357907.2020.1844893
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The outbreak of COVID-19 pandemia is a major health worldwide concern. Patients with cancer might have a worse outcome, because of the immunosuppression determined by the tumor itself and anti-cancer treatments, including chemotherapy and radiotherapy. The impact and course of viral infection in patients receiving immunotherapy remains unknown. We report the case of a patient with metastatic melanoma, long responder to anti PD-1 blockade who got infected with Sars CoV-2, recovering without sequelae. A critical review of literature was performed. Limited data available in literature support the possibility to continue the immunotherapy in patients with cancer under control.
引用
收藏
页码:9 / 14
页数:6
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