Nicotinamide and the skin

被引：70

作者：

Chen, Andrew C. ^{[1
,2
]}

Damian, Diona L. ^{[1
,2
,3
]}

机构：

[1] Univ Sydney, Cent Clin Sch, Bosch Inst, Discipline Dermatol, Sydney, NSW 2006, Australia

[2] Royal Prince Alfred Hosp, Sydney Canc Ctr, Dept Dermatol, Sydney, NSW, Australia

[3] Melanoma Inst Australia, Sydney, NSW, Australia

来源：

AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2014年 / 55卷 / 03期

关键词：

nicotinamide; skin cancer; skin disease; RADIATION-INDUCED IMMUNOSUPPRESSION; TRANSEPIDERMAL WATER-LOSS; TOPICAL NICOTINAMIDE; HUMAN KERATINOCYTES; ATOPIC-DERMATITIS; ACTINIC KERATOSES; STRATUM-CORNEUM; NIACINAMIDE; ULTRAVIOLET; TETRACYCLINE;

D O I：

10.1111/ajd.12163

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Nicotinamide, an amide form of vitamin B3, boosts cellular energy and regulates poly-ADP-ribose-polymerase 1, an enzyme with important roles in DNA repair and the expression of inflammatory cytokines. Nicotinamide shows promise for the treatment of a wide range of dermatological conditions, including autoimmune blistering disorders, acne, rosacea, ageing skin and atopic dermatitis. In particular, recent studies have also shown it to be a potential agent for reducing actinic keratoses and preventing skin cancers.

引用

页码：169 / 175

页数：7

共 65 条

[1]

[Anonymous], 2004, NOUVELLES DERMATOLOG

[2] HOW MUCH MELANOMA IS CAUSED BY SUN EXPOSURE [J].