LSVT-BIG Improves UPDRS III Scores at 4 Weeks in Parkinson's Disease Patients with Wearing Off: A Prospective, Open-Label Study

被引：8

作者：

Ueno, Tatsuya ^{[1
]}

Sasaki, Megumi ^{[2
]}

Nishijima, Haruo ^{[1
]}

Funamizu, Yukihisa ^{[1
]}

Kon, Tomoya ^{[1
]}

Haga, Rie ^{[1
]}

Arai, Akira ^{[1
]}

Suzuki, Chieko ^{[1
]}

Nunomura, Jin-ichi ^{[1
]}

Baba, Masayuki ^{[1
]}

Tomiyama, Masahiko ^{[1
]}

机构：

[1] Aomori Prefectural Cent Hosp, Dept Neurol, Aomori, Japan

[2] Aomori Prefectural Cent Hosp, Dept Rehabil, Aomori, Japan

来源：

PARKINSONS DISEASE | 2017年 / 2017卷

关键词：

QUALITY-OF-LIFE; EXERCISE; PEOPLE; LEVODOPA;

D O I：

10.1155/2017/8130140

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The efficacy of LSVT-BIG for advanced Parkinson's disease (PD) patients with wearing off remains to be determined. Therefore, we evaluated whether LSVT-BIG improves motor disability in eight PD patients with wearing off. Unified Parkinson's Disease Rating Scale (UPDRS) scores, daily off time, andmobility assessments were evaluated during the "on" time before and after the LSVT-BIG course. LSVT-BIG significantly improved UPDRS III scores at 4 weeks and UPDRS II scores in the "off" state at 12 weeks, with no changes in the other measures. The findings suggest that LSVT-BIG may be an effective therapy for advanced PD patients with wearing off.

引用

页数：4

共 18 条

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