NaIO4-Catalyzed One-Pot Synthesis of Dihydropyrimidinones at Room Temperature under Solvent-Free Conditions

被引:21
|
作者
Jing, X. [1 ]
Li, Z. [1 ]
Pan, X. [1 ]
Shi, Y. [1 ]
Yan, C. [1 ]
机构
[1] Yangzhou Univ, Coll Chem & Chem Engn, Yangzhou 225002, Peoples R China
基金
中国国家自然科学基金;
关键词
Pyrimidinones; Sodium periodate; Biginelli reaction; Solvent-free conditions; BIGINELLI; PROTOCOL;
D O I
10.1007/BF03246529
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Sodium periodate efficiently catalyzed the three-component Biginelli reaction of an aldehyde, alpha beta-keto ester or beta-keto ketone, and urea or thiourea at room temperature under solvent-free conditions and afforded the corresponding 3,4-dihydropyrimidine-2-(1H)-ones in excellent yields.
引用
收藏
页码:514 / 518
页数:5
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