Fourier transform infrared spectroscopic studies on the normal and malignant esophagus tissues

Nine pairs of human normal and malignant esophagus tissues were studied by Fourier transform infrared (FTIR) spectroscopy. The results show that there are obvious spectral differences between them. The changes involving nu(s)(PO(2)(-)) and nu(ss) (PO(2)(-)) in nucleic acid (DNA, RNA) nu(s)(CH(2)) nu(ss) (CH(3)), delta(CH(2)) and delta(s)(CH(3)) in membrane lipids and the C - O stretching mode in cell proteins were discussed. In addition, the changes of structure of hydrogen-bonding of nucleic acid (DNA, RNA) and cell proteins and the packing and the conformational. structure of the mernbrance lipids were analysed further.