Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases

被引：36
作者：
Franca, Paulo H. B. [1 ]
Barbosa, Daniel P. [2 ]
da Silva, Daniel L. [1 ]
Ribeiro, Eurica A. N. [2 ]
Santana, Antonio E. G. [1 ]
Santos, Barbara V. O. [3 ]
Barbosa-Filho, Jose M. [3 ]
Quintans, Jullyana S. S. [4 ]
Barreto, Rosana S. S. [4 ]
Quintans-Junior, Lucindo J. [4 ]
de Araujo-Junior, Joao X. [1 ,2 ]
机构：
[1] Univ Fed Alagoas, Inst Chem & Biotechnol, BR-57072970 Maceio, AL, Brazil
[2] Univ Fed Alagoas, Sch Nursing & Pharm, BR-57072970 Maceio, AL, Brazil
[3] Univ Fed Paraiba, Lab Pharmaceut Technol, BR-58051900 Joao Pessoa, Paraiba, Brazil
[4] Univ Fed Sergipe, Dept Physiol, BR-49000100 Sao Cristivai, SE, Brazil
来源：
BIOMED RESEARCH INTERNATIONAL | 2014年 / 2014卷
关键词：
NATURAL-PRODUCTS; BETA-CARBOLINE; TROPANE ALKALOIDS; SPONGE; DERIVATIVES; COMPILATION; FLAVONOIDS; INHIBITOR; ANALOGS; PLANTS;
D O I：
10.1155/2014/375423
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemotherapeutic agents. Furthermore, the emerging resistance against these drugs makes it urgently necessary to discover and develop new, safe and, effective anti-infective agents. In this regard, the aim of this review is to highlight indole alkaloids from marine sources which have been shown to demonstrate activity against infectious diseases.
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页数：12
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