A facile one-pot synthesis of N-substituted tetrahydroquinolines

被引：19

作者：

Babu, Thelagathoti Hari ^{[1
]}

Shanthi, Gnanamani ^{[1
]}

Perumal, Paramasivan T. ^{[1
]}

机构：

[1] Cent Leather Res Inst, Div Organ Chem, Madras 600020, Tamil Nadu, India

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 24期

关键词：

Quinoline; Hantzsch dihydropyridine; N-Substituted tetrahydroquinoline; IRIDIUM-CATALYZED HYDROGENATION; DIELS-ALDER REACTIONS; NADH MODEL-COMPOUND; 1,2,3,4-TETRAHYDRO DERIVATIVES; FARNESYLTRANSFERASE INHIBITORS; HANTZSCH 1,4-DIHYDROPYRIDINE; REDUCTIVE AMINATION; QUINOLINES; ACID; BENZOQUINONE;

D O I：

10.1016/j.tetlet.2009.03.181

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An uncatalyzed one-pot synthesis of N-substituted tetrahydroquinolines was achieved in good yields by the reaction of quinoline and alkyl/acyl halides with Hantzsch dihydropyridine ester under mild reaction conditions. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：2881 / 2884

页数：4

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