An autopsy case of bacterial septic shock 12 years following ABO-incompatible renal transplantation

被引:5
作者
Okamoto, M [1 ]
Omori, Y
Ichida, M
Nobori, S
Higuchi, A
Kadotani, Y
Akioka, K
Itoh, K
Fushiki, S
Yoshimura, N
机构
[1] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Transplantat & Regenerat Surg, Kamigyo Ku, Kyoto 6028566, Japan
[2] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Pathol & Appl Neurobiol, Kamigyo Ku, Kyoto 6028566, Japan
关键词
ABO-incompatible renal transplantation; chronic allograft nephropathy; hepatitis C; septic shock;
D O I
10.1111/j.1399-0012.2004.00247.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
We report the case of an ABO-incompatible kidney transplant recipient who died suddenly following a good transplant course of 12 years. For 10 years after transplantation, the graft function had been stable (s-Cr: 1.0-1.5 mg/dL), although chronic hepatitis C had developed, with elevation of transaminase. In the 11th year, he was admitted into the hospital with low-grade fever and general fatigue. Jaundice and anaemia progressed, and he died 2 months after admission. The autopsy diagnosis was: (1) post-renal transplantation state, (2) phlegmonous enterocolitis with septic infarction, (3) cellulitis and necrotic myositis, and (4) sepsis. The transplanted kidney graft showed well-preserved glomeruli and tubules, corresponding to chronic allograft nephropathy (CAN) grade I (ci1, ct1, cv1), according to the Banff classification. The pathological changes observed in this long-surviving ABO-incompatible kidney graft were similar to those of an ABO-compatible graft, although its degree was milder.
引用
收藏
页码:44 / 49
页数:6
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