Thyrotoxicosis due to metastatic papillary thyroid cancer in a patient with Graves' disease

被引:13
作者
Basaria, S [1 ]
Salvatori, R [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Div Endocrinol & Metab, Dept Med, Baltimore, MD 21287 USA
关键词
thyroid cancer; thyrotoxicosis;
D O I
10.1007/BF03345090
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thyrotoxicosis resulting from functional thyroid cancer metastases is extremely rare, and is mostly caused by follicular cancer. The lesions causing thyrotoxicosis are usually bulky and extensive. We report here a patient with Graves' disease and concomitant papillary thyroid cancer who developed metastases causing symptomatic thyrotoxicosis. His serum titers of thyroid stimulating Ig (TSIs) were elevated. We believe that TSIs were responsible for thyrotoxicosis by stimulating hormonogenesis in the metastatic lesions. (C) 2002, Editrice Kurtis.
引用
收藏
页码:639 / 642
页数:4
相关论文
共 21 条
[1]   Graves' disease and recurrent ectopic thyroid tissue [J].
Basaria, S ;
Cooper, DS .
THYROID, 1999, 9 (12) :1261-1264
[2]   INCREASED AGGRESSIVENESS OF THYROID-CANCER IN PATIENTS WITH GRAVES-DISEASE [J].
BELFIORE, A ;
GAROFALO, MR ;
GIUFFRIDA, D ;
RUNELLO, F ;
FILETTI, S ;
FIUMARA, A ;
IPPOLITO, O ;
VIGNERI, R .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1990, 70 (04) :830-835
[3]  
CERLETTY JM, 1979, JAMA-J AM MED ASSOC, V242, P269, DOI 10.1001/jama.242.3.269
[4]  
Clark O H, 1981, World J Surg, V5, P39
[5]   Thyroid controversy-stimulating antibodies [J].
Davies, TF ;
Roti, E ;
Braverman, LE ;
Degroot, LJ .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (11) :3777-3781
[6]   HYPER-THYROIDISM INDUCED BY SECONDARY CARCINOMA IN THYROID [J].
EDMONDS, CJ ;
THOMPSON, BD .
CLINICAL ENDOCRINOLOGY, 1978, 8 (05) :411-415
[7]   THE ROLE OF THYROID-STIMULATING ANTIBODIES OF GRAVES-DISEASE IN DIFFERENTIATED THYROID-CANCER [J].
FILETTI, S ;
BELFIORE, A ;
AMIR, SM ;
DANIELS, GH ;
IPPOLITO, O ;
VIGNERI, R ;
INGBAR, SH .
NEW ENGLAND JOURNAL OF MEDICINE, 1988, 318 (12) :753-759
[8]   SEVERE HYPERTHYROIDISM DUE TO METASTATIC PAPILLARY THYROID-CARCINOMA WITH FAVORABLE OUTCOME [J].
GIRELLI, ME ;
CASARA, D ;
RUBELLO, D ;
PELIZZO, MR ;
BUSNARDO, B ;
ZILIOTTO, D .
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1990, 13 (04) :333-337
[9]  
KASAGI K, 1994, CLIN ENDOCRINOL, V40, P429
[10]  
Lorberboym M, 1996, J NUCL MED, V37, P1532