An efficient one-pot synthesis of polyhydroquinolines at room temperature using HY-Zeolite

被引:96
作者
Das, Biswanath [1 ]
Ravikanth, Bommena [1 ]
Ramu, Ravirala [1 ]
Rao, Bommena Vittal [1 ]
机构
[1] Indian Inst Chem Technol, Div Organ Chem 1, Hyderabad 500007, Andhra Pradesh, India
关键词
polyhydroquinoline; four-component coupling; one-pot conversion; HY-zeolite; heterogeneous catalyst;
D O I
10.1248/cpb.54.1044
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
An efficient one-pot synthesis of polyhydroquinolines by four-component coupling reactions of aldehydes, ethyl acetoacetate, dimedone and ammonium acetate in the presence of HY-zeolite at ambient temperature has been achieved. The conversions took shorter times to form the products in excellent yields. HY-zeolite can be recovered and reused.
引用
收藏
页码:1044 / 1045
页数:2
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