Role of Matrix Metalloproteinases in Skin Ageing

被引：105

作者：

Sardy, Miklos ^{[1
]}

机构：

[1] Univ Munich, Dept Dermatol & Allergol, D-80337 Munich, Germany

来源：

CONNECTIVE TISSUE RESEARCH | 2009年 / 50卷 / 02期

关键词：

Matrix Metalloproteinases; Skin Ageing; Connective Tissue Degradation; Photoageing; Chronological Ageing; Extracellular Matrix; TISSUE INHIBITOR; REPERFUSION INJURY; TOPICAL TRETINOIN; HYDROGEN-PEROXIDE; RETINOIC ACID; CELL-GROWTH; TNF-ALPHA; IN-VIVO; ACTIVATION; EXPRESSION;

D O I：

10.1080/03008200802585622

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Matrix metalloproteinases are a family of ubiquitous endopeptidases playing a role in many different physiological and pathological processes in the skin. They are also involved in cutaneous ageing. This review summarizes the features and regulation of these enzymes and presents an overview of the molecular mechanisms of both intrinsic and extrinsic skin ageing presents. The role of matrix metalloproteinases in skin ageing is discussed in detail.

引用

页码：132 / 138

页数：7

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