Serum B12, homocysteine, and anti-parietal cell antibody levels in children with autism

被引：7

作者：

Erden, Semih ^{[1
]}

Akbas Ileri, Betul ^{[1
]}

Sadic Celikkol, Cagla ^{[1
]}

Nalbant, Kevser ^{[2
]}

Kilinc, Ibrahim ^{[3
]}

Yazar, Abdullah ^{[4
]}

机构：

[1] Necmettin Erbakan Univ, Fac Med, Dept Child & Adolescent Psychiat, Konya, Turkey

[2] Hacettepe Univ, Fac Med, Dept Child & Adolescent Psychiat, Ankara, Turkey

[3] Necmettin Erbakan Univ, Fac Med, Dept Biochem, Konya, Turkey

[4] Necmettin Erbakan Univ, Fac Med, Dept Child Hlth & Dis, Konya, Turkey

来源：

INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE | 2022年 / 26卷 / 01期

关键词：

Autism spectrum disorder; children; vitamin B12; homocysteine; anti-parietal cell antibody;

D O I：

10.1080/13651501.2021.1906906

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Aims To compare vitamin B12, homocysteine, and anti-parietal cell antibody (APCA) levels between children with ASD and controls, paired in terms of age, sex, and socioeconomic level. Methods The research group consisted of 69 children, 36 with ASD and 33 controls. The severity of ASD was determined using the Childhood Autism Rating Scale (CARS). Serum vitamin B12, homocysteine and human anti-parietal cell levels were analysed using enzyme-linked immunosorbent assay. Results The serum vitamin B12 and homocysteine levels in children with ASD were lower than in the control group, but there was no significant difference in terms of APCA levels. Conclusions Deficiencies in micronutrients, such as B12, may play a role in the pathogenesis and clinical symptoms of autism. However, it is believed that these parameters should be analysed in a wider population to clarify their effect on the aetiology of ASD.

引用

页码：8 / 13

页数：6

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