The neurophysiology of unmyelinated tactile afferents

被引：377

作者：

Olausson, Hakan ^{[1
]}

Wessberg, Johan ^{[1
]}

Morrison, India ^{[1
]}

McGlone, Francis ^{[2
]}

Vallbo, Ake ^{[1
]}

机构：

[1] Univ Gothenburg, Inst Neurosci & Physiol, Gothenburg, Sweden

[2] Univ Liverpool, Dept Neurol Sci, Liverpool L69 3BX, Merseyside, England

来源：

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS | 2010年 / 34卷 / 02期

基金：

瑞典研究理事会;

关键词：

C fiber; Mechanoafferent; Touch; Insular cortex; Emotion; HUMAN HAIRY SKIN; SUBSTANTIA-GELATINOSA; SIGNAL TOUCH; C FIBERS; PAIN; MECHANORECEPTORS; NERVE; SUMATRIPTAN; NUCLEUS; NEURONS;

D O I：

10.1016/j.neubiorev.2008.09.011

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

CT (C tactile) afferents are a distinct type of unmyelinated, low-threshold mechanoreceptive units existing in the hairy but not glabrous skin of humans and other mammals. Evidence from patients lacking myelinated tactile afferents indicates that signaling in these fibers activate the insular cortex. Since this system is poor in encoding discriminative aspects of touch, but well-suited to encoding slow, gentle touch, CT fibers in hairy skin may be part of a system for processing pleasant and socially relevant aspects of touch. CT fiber activation may also have a role in pain inhibition. This review outlines the growing evidence for unique properties and pathways of CT afferents. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：185 / 191

页数：7

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