Formal Total Synthesis of Actinoranone and Asymmetric Synthesis of Labda-7,13-(E)-dien-15-ol

被引：13

作者：

Novaes, Luiz F. T. ^{[1
]}

Pastre, Julio C. ^{[1
]}

机构：

[1] Univ Campinas UNICAMP, Inst Chem, POB 6154, BR-13084971 Campinas, SP, Brazil

来源：

ORGANIC LETTERS | 2017年 / 19卷 / 12期

基金：

巴西圣保罗研究基金会;

关键词：

STEREOCHEMICAL REVISION; STRUCTURE ELUCIDATION; CHEMICAL-SYNTHESIS; NATURAL-PRODUCTS; DESIGN; DERIVATIVES;

D O I：

10.1021/acs.orglett.7b01287

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The syntheses of the polyketide terpenoid fragments of actinoranone are reported in a concise fashion, relying on catalytic methods. Minimization on the use of protecting groqps: and redox reactions allowed the synthesis of the carbon backbone of actinoranone in 20 steps (11 steps for LLS). The asymmetric Synthesis of labda-7,13-(E)-dien-15-ol is also disclosed.

引用

页码：3163 / 3166

页数：4

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