Hydrochlorothiazide use and risk of skin cancers: A systematic review

被引：2

作者：

Becquart, O. ^{[1
]}

Guillot, B. ^{[1
]}

Bourrain, J-L ^{[1
]}

Duflos, C. ^{[2
]}

Du-Thanh, A. ^{[1
]}

机构：

[1] Hop St Eloi, Dept Dermatol, F-34295 Montpellier 5, France

[2] Univ Montpellier, Dept Informat Med, CHU Montpellier, F-34295 Montpellier, France

来源：

REVUE DE MEDECINE INTERNE | 2019年 / 40卷 / 09期

关键词：

Hydrochlorothiazide; Skin neoplasm; Epidemiology; BASAL-CELL CARCINOMA; ANTIHYPERTENSIVE DRUGS; DIURETICS;

D O I：

10.1016/j.revmed.2019.04.008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The risk of skin cancer induced by photosensiting drugs is well known. An association between hydrochlorothiazide use and skin cancer has been recently published in some epidemiological studies. A systematic review of case-control or prospectives cohorts showed an increased risk of cutaneous squamous cell carcinoma even if some confusing factors such as tobacco smoking was not analysed. Results are more conflicting for basal cell carcinoma or melanoma. These results do not modify the benefit/risk ratio but should lead to propose preventive mesures: identification of high risk population, avoidance of this drug if possible in immunocompromised patients or with previous skin cancer, regular skin examination in case of long term use of hydrochlorothiazide. (C) 2019 Societe Nationale Francaise de Medecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.

引用

页码：617 / 622

页数：6

共 16 条

[1] THIAZIDE-INDUCED PHOTOSENSITIVITY - A STUDY OF 33 SUBJECTS [J].

ADDO, HA ;

FERGUSON, J ;

FRAINBELL, W .

BRITISH JOURNAL OF DERMATOLOGY, 1987, 116 (06) :749-760

[2]

Agence nationale de securite du medicament et des produits de sante, 2018, RISQ CANC PEAU ASS M

[3] Known and potential new risk factors for skin cancer in European populations: a multicentre case-control study [J].

de Vries, E. ;

Trakatelli, M. ;

Kalabalikis, D. ;

Ferrandiz, L. ;

Ruiz-de-Casas, A. ;

Moreno-Ramirez, D. ;

Sotiriadis, D. ;

Ioannides, D. ;

Aquilina, S. ;

Apap, C. ;

Micallef, R. ;

Scerri, L. ;

Ulrich, M. ;

Pitkanen, S. ;

Saksela, O. ;

Altsitsiadis, E. ;

Hinrichs, B. ;

Magnoni, C. ;

Fiorentini, C. ;

Majewski, S. ;

Ranki, A. ;

Stockfleth, E. ;

Proby, C. .

BRITISH JOURNAL OF DERMATOLOGY, 2012, 167 :1-13

[4] A Multistep Voriconazole-Related Phototoxic Pathway May Lead to Skin Carcinoma: Results From a French Nationwide Study [J].

Epaulard, Olivier ;

Villier, Celine ;

Ravaud, Philippe ;

Chosidow, Olivier ;

Blanche, Stephane ;

Mamzer-Bruneel, Marie-France ;

Thiebaut, Anne ;

Leccia, Marie-Therese ;

Lortholary, Olivier .

CLINICAL INFECTIOUS DISEASES, 2013, 57 (12) :E182-E188

[5] Antihypertensive Drugs and Lip Cancer in Non-Hispanic Whites [J].

Friedman, Gary D. ;

Asgari, Maryam M. ;

Warton, E. Margaret ;

Chan, James ;

Habel, Laurel A. .

ARCHIVES OF INTERNAL MEDICINE, 2012, 172 (16) :1246-1251

[6] Cutaneous Epithelial Tumors Induced by Vemurafenib Involve the MAPK and Pi3KCA Pathways but Not HPV nor HPyV Viral Infection [J].

Frouin, Eric ;

Guillot, Bernard ;

Larrieux, Marion ;

Tempier, Ariane ;

Boulle, Nathalie ;

Foulongne, Vincent ;

Girard, Celine ;

Costes, Valerie ;

Solassol, Jerome .

PLOS ONE, 2014, 9 (10)

[7] Increased phototoxicity of hydrochlorothiazide by photodegradation [J].

Han, KD ;

Bark, KM ;

Heo, EP ;

Lee, JK ;

Kang, JS ;

Kim, TH .

PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE, 2000, 16 (03) :121-124

[8] Use of photosensitising diuretics and risk of skin cancer: a population-based case-control study [J].

Jensen, A. O. ;

Thomsen, H. F. ;

Engebjerg, M. C. ;

Olesen, A. B. ;

Sorensen, H. T. ;

Karagas, M. R. .

BRITISH JOURNAL OF CANCER, 2008, 99 (09) :1522-1528

[9] Hydrochlorothiazide Enhances UVA-Induced DNA Damage [J].

Kunisada, Makoto ;

Masaki, Taro ;

Ono, Ryusuke ;

Morinaga, Hironobu ;

Nakano, Eiji ;

Yogianti, Flandiana ;

Okunishi, Kunihiro ;

Sugiyama, Hiroshi ;

Nishigori, Chikako .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2013, 89 (03) :649-654

[10] Smoking and the Risk of Nonmelanoma Skin Cancer Systematic Review and Meta-analysis [J].

Leonardi-Bee, Jo ;

Ellison, Thomas ;

Bath-Hextall, Fiona .

ARCHIVES OF DERMATOLOGY, 2012, 148 (08) :939-946

← 1 2 →