Tunable Antibacterial Coatings That Support Mammalian Cell Growth

被引:134
作者
Vasilev, Krasimir [1 ]
Sah, Vasu [1 ,2 ]
Anselme, Karine [3 ]
Ndi, Chi [2 ]
Mateescu, Mihaela [3 ]
Dollmann, Bjoern [2 ]
Martinek, Petr [2 ]
Ys, Hardi [2 ]
Ploux, Lydie [3 ]
Griesser, Hans J. [2 ]
机构
[1] Univ S Australia, Mawson Inst, Mawson Lakes, SA 5095, Australia
[2] Univ S Australia, Ian Wark Res Inst, Mawson Lakes, SA 5095, Australia
[3] Univ Haute Alsace, Inst Sci Mat Mulhouse, Mulhouse, France
关键词
PLASMA POLYMER-COATINGS; INTENSIVE-CARE UNITS; ANTIBIOTIC-RESISTANCE; SILVER NANOPARTICLES; CORROSION PROTECTION; INFECTION; DEPOSITION; AMINE; COLONIZATION; GENERATION;
D O I
10.1021/nl903274q
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Bacterial infections present an enormous problem causing human suffering and cost burdens to healthcare systems worldwide. Here we present novel tunable antibacterial coatings which completely inhibit bacterial colonization by Staphylococcus epidermidis but allow normal adhesion and spreading of osteoblastic cells. The coatings are based on at-nine plasma polymer films loaded with silver nanoparticles. The method of preparation allows flexible control over the amount of loaded silver nanoparticles and the rate of release of silver ions.
引用
收藏
页码:202 / 207
页数:6
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