Evaluation of Autonomic Nervous System function in Children with Overactive Bladder Syndrome

被引：7

作者：

Demir, Aysegul Dogan ^{[1
]}

Gursoy, Azize Esra ^{[2
]}

Goknar, Nilufer ^{[3
]}

Uzuner, Selcuk ^{[1
]}

Ozkaya, Emin ^{[4
]}

Erenberk, Ufuk ^{[1
]}

Vehapoglu, Aysel ^{[1
]}

Dundaroz, Mehmet Rusen ^{[1
]}

Oktem, Faruk ^{[3
]}

机构：

[1] Bezmialem Vakif Univ, Dept Pediat, Fac Med, Istanbul, Turkey

[2] Bezmialem Vakif Univ, Dept Neurol, Fac Med, Istanbul, Turkey

[3] Bezmialem Vakif Univ, Dept Pediat Cardiol, Fac Med, Istanbul, Turkey

[4] Bezmialem Vakif Univ, Dept Pediat Allergy & Immunol, Fac Med, Istanbul, Turkey

来源：

NEUROUROLOGY AND URODYNAMICS | 2017年 / 36卷 / 03期

关键词：

autonomic dysfunction; children; overactive bladder; heart rate interval variation; HEART-RATE-VARIABILITY; URINARY-INCONTINENCE; SYMPTOMS; WOMEN; PATHOPHYSIOLOGY; ENURESIS;

D O I：

10.1002/nau.22993

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose We aimed to evaluate the autonomic nervous system activity in children with overactive bladder (OAB) syndrome.Methods Included in the study were 40 children with overactive bladder and 28 healthy controls. Autonomic tests were performed on all participants, including heart rate interval variation (RRIV), heart rate response to valsalva maneuver, and sympathetic skin response (SSR).Results Mean valsalva rates in the overactive bladder and control groups were 1.530.29 and 1.30 +/- 0.18, respectively, a statistically significant difference (P<0.001). Also significantly different were deep breathing RRIV values of the study and control groups: 56.65 +/- 14.66 and 47.92 +/- 10.15, respectively (P=0.008). No statistical differences were found in SSR when OAB patients were compared with controls (P>0.05).Conclusions This study demonstrated a parasympathetic hyperactivity in children with OAB, results suggesting a dysfunction in their autonomic nervous systems. (C) 2016 Wiley Periodicals, Inc.

引用

页码：673 / 676

页数：4

共 26 条

[11] Overactive bladder in children. Part 1: Pathophysiology [J].

Franco, Israel .

JOURNAL OF UROLOGY, 2007, 178 (03) :761-768

[12]

Hainsworth R., 1995, Heart Rate Variability, P3

[13]

Haylen BT, 2010, INT UROGYNECOL J, V21, P5, DOI [10.1007/s00192-009-0976-9, 10.1590/S1677-55382010000100032]

[14] Autonomic nervous system activity during bladder filling assessed by heart rate variability analysis in women with idiopathic overactive bladder syndrome or stress urinary incontinence [J].

Hubeaux, Katelyne ;

Deffieux, Xavier ;

Ismael, Samer Sheikh ;

Raibaut, Patrick ;

Amarenco, Gerard .

JOURNAL OF UROLOGY, 2007, 178 (06) :2483-2487

[15] Evidence for Autonomic Nervous System Dysfunction in Females With Idiopathic Overactive Bladder Syndrome [J].

Hubeaux, Katelyne ;

Deffieux, Xavier ;

Raibaut, Patrick ;

Le Breton, Frederique ;

Jousse, Marylene ;

Amarenco, Gerard .

NEUROUROLOGY AND URODYNAMICS, 2011, 30 (08) :1467-1472

[16]

Kim Joon Chul, 2010, Int Neurourol J, V14, P232, DOI 10.5213/inj.2010.14.4.232

[17] Nonselective Blocking of the Sympathetic Nervous System Decreases Detrusor Overactivity in Spontaneously Hypertensive Rats [J].

Kim, Khae-Hawn ;

Jin, Long-Hu ;

Choo, Gwoan-Youb ;

Lee, Hun-Jae ;

Choi, Bo-Hwa ;

Kwak, Jiyeon ;

Yoon, Sang-Min ;

Park, Chang-Shin ;

Lee, Tack .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2012, 13 (04) :5048-5059

[18]

Lazzeri Massimo, 2006, Int. braz j urol., V32, P620, DOI 10.1590/S1677-55382006000600002

[19] A noninvasive evaluation of autonomic nervous system dysfunction in women with an overactive bladder [J].

Liao, Wen-Chien ;

Jaw, Fu-Shan .

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2010, 110 (01) :12-17

[20] Studies of the pathophysiology of idiopathic detrusor instability: The physiological properties of the detrusor smooth muscle and its pattern of innervation [J].

Mills, IW ;

Greenland, JE ;

McMurray, G ;

McCoy, R ;

Ho, KMT ;

Noble, JG ;

Brading, AF .

JOURNAL OF UROLOGY, 2000, 163 (02) :646-651

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