Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery

被引：157
作者：
de Ligt, RAF [1 ]
Kourounakis, AP [1 ]
Ijzerman, AP [1 ]
机构：
[1] Leiden Amsterdam Ctr Drug Res, Div Med Chem, NL-2300 RA Leiden, Netherlands
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 2000年 / 130卷 / 01期
关键词：
GPCR; inverse agonism; neutral antagonist; negative efficacy; review; implications drug discovery;
D O I：
10.1038/sj.bjp.0703311
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：1 / 12
页数：12
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