Osteonecrosis of the jaws in patients treated with intravenous bisphosphonates (BRONJ): A concise update

被引：58
作者：
Bagan, Jose [1 ,2 ]
Scully, Crispian [3 ,4 ]
Sabater, Vicente
Jimenez, Yolanda [2 ]
机构：
[1] Hosp Gen Univ, Serv Estomatol, Valencia 46014, Spain
[2] Univ Valencia, Valencia, Spain
[3] UCL, EDI, London, England
[4] WHO Collaborating Ctr Res Educ & Serv Oral Hlth D, London, England
来源：
ORAL ONCOLOGY | 2009年 / 45卷 / 07期
关键词：
Osteonecrosis; Bisphosphonates; Cancer; Jaws; MULTIPLE-MYELOMA; RISK-FACTORS; HYPERBARIC-OXYGEN; CANCER; ZOLEDRONATE; PREVENTION; PREDICTION; FREQUENCY; THERAPY; BREAST;
D O I：
10.1016/j.oraloncology.2009.01.002
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a severe complication seen most frequently in patients on intravenous bisphosphonates treatment for malignant diseases. High potency bisphosphonates are generally implicated and risk factors also include dental extractions. Prevention is of paramount importance. Management is controversial but there is little evidence basis and the consensus is to be conservative. Recent advances in this area are summarised in this concise review. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：551 / 554
页数：4
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