Multivalency in the gas phase: The study of dendritic aggregates by mass spectrometry

被引:54
作者
Broeren, MAC [1 ]
van Dongen, JLJ [1 ]
Pittelkow, M [1 ]
Christensen, JB [1 ]
van Genderen, MHP [1 ]
Meijer, EW [1 ]
机构
[1] Eindhoven Univ Technol, Lab Macromol & Organ Chem, NL-5600 MB Eindhoven, Netherlands
关键词
dendrimers; dynamic libraries; host-guest chemistry; mass spectrometry; supramolecular chemistry;
D O I
10.1002/anie.200453707
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Selective guest ejection: Up to eight guest molecules are assembled at the periphery of a third-generation dendrimer. Collision-induced dissociation mass spectrometry has demonstrated that the guests are removed very selectively in a one-by-one manner (see spectrum).
引用
收藏
页码:3557 / 3562
页数:6
相关论文
共 36 条
[1]  
[Anonymous], 2001, DENDRIMERS OTHER DEN
[2]   Threshold collision-induced dissociations for the determination of accurate gas-phase binding energies and reaction barriers [J].
Armentrout, PB .
MODERN MASS SPECTROMETRY, 2003, 225 :233-262
[3]  
Baars MWPL, 2000, ANGEW CHEM INT EDIT, V39, P4262, DOI 10.1002/1521-3773(20001201)39:23<4262::AID-ANIE4262>3.0.CO
[4]  
2-Y
[5]  
Baars MWPL, 2000, ANGEW CHEM, V112, P4432
[6]   Electrospray ionization mass spectrometry of oligonucleotide complexes with drugs, metals, and proteins [J].
Beck, JL ;
Colgrave, ML ;
Ralph, SF ;
Sheil, MM .
MASS SPECTROMETRY REVIEWS, 2001, 20 (02) :61-87
[7]  
Boas U, 2002, CHEMBIOCHEM, V3, P433, DOI 10.1002/1439-7633(20020503)3:5<433::AID-CBIC433>3.0.CO
[8]  
2-0
[9]   About dendrimers: Structure, physical properties, and applications [J].
Bosman, AW ;
Janssen, HM ;
Meijer, EW .
CHEMICAL REVIEWS, 1999, 99 (07) :1665-1688
[10]   ELECTROSPRAY IONIZATION FOR MASS-SPECTROMETRY OF LARGE BIOMOLECULES [J].
FENN, JB ;
MANN, M ;
MENG, CK ;
WONG, SF ;
WHITEHOUSE, CM .
SCIENCE, 1989, 246 (4926) :64-71