Prognostic factors related with survival in patients with pancreatic adenocarcinoma

被引：112
作者：
Bilici, Ahmet [1 ]
机构：
[1] Istanbul Medipol Univ, Fac Med, Dept Med Oncol, TR-34214 Istanbul, Turkey
来源：
WORLD JOURNAL OF GASTROENTEROLOGY | 2014年 / 20卷 / 31期
关键词：
Pancreatic cancer; Prognostic factors; Survival; Carbohydrate antigen 19-9; Treatment; LYMPH-NODE RATIO; BODY-MASS INDEX; PREOPERATIVE PLATELET COUNT; LONG-TERM SURVIVAL; DUCTAL ADENOCARCINOMA; CANCER-PATIENTS; LEVELS PREDICT; RESECTION MARGINS; POOR-PROGNOSIS; TUMOR-MARKERS;
D O I：
10.3748/wjg.v20.i31.10802
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
The prognosis in patients with pancreatic cancer is poor and this cancer is the fourth leading cause of cancer-related death worldwide. Although surgical resection is the only curative treatment of choice for pancreatic cancer, the majority of patients are diagnosed at an advanced stage, thus only 10%-15% of them are suitable for curative resection and the overall survival is less than 5%. Chemotherapy for metastatic disease is to palliate symptoms of patients and to improve survival. Therefore, prognostic factors are important and a correct definition of poor prognostic factors may help to guide more aggressive adjuvant or aggressive treatment protocols in patients with pancreatic cancer. This article reviews the prognostic factors affecting survival of patients with pancreatic cancer in the light of recent advances in the literature. (C) 2014 Baishideng Publishing Group Inc. All rights reserved.
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收藏
页码：10802 / 10812
页数：11
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