THROMBOLYTICS FOR HYPERACUTE STROKE IN CHILDREN

被引:3
作者
Amlie-Lefond, Catherine
Fullerton, Heather J. [1 ]
机构
[1] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA
关键词
thrombolytics; stroke; TISSUE-PLASMINOGEN ACTIVATOR; ARTERIAL ISCHEMIC-STROKE; THERAPY; INTRAARTERIAL; CHILDHOOD; PROUROKINASE; MANAGEMENT; DISEASE; PROACT; SYSTEM;
D O I
10.1080/08880010902773230
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Intravenous tissue plasminogen activator (tPA) has changed the landscape of acute stroke care in adults, but remains unstudied in children. Developmental differences in both stroke etiologies and the hematologic system may alter the risk benefit ratio of this drug when applied to stroke in children.
引用
收藏
页码:103 / 107
页数:5
相关论文
共 31 条
[1]  
AMLIELEFOND C, 2007, J THROMB HAEMOST S2, V5, P579
[2]   MATURATION OF THE HEMOSTATIC SYSTEM DURING CHILDHOOD [J].
ANDREW, M ;
VEGH, P ;
JOHNSTON, M ;
BOWKER, J ;
OFOSU, F ;
MITCHELL, L .
BLOOD, 1992, 80 (08) :1998-2005
[3]   Use of tissue plasminogen activator in a stroke after radiofrequency ablation of a left-sided accessory pathway [J].
Cannon, BC ;
Kertesz, NJ ;
Friedman, RA ;
Fenrich, AL .
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY, 2001, 12 (06) :723-725
[4]   Successful use of rt-PA in pediatric stroke [J].
Carlson, MD ;
Leber, S ;
Deveikis, J ;
Silverstein, FS .
NEUROLOGY, 2001, 57 (01) :157-158
[5]   PROACT: A phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke [J].
del Zoppo, GJ ;
Higashida, RT ;
Furlan, AJ ;
Pessin, MS ;
Rowley, HA ;
Gent, M .
STROKE, 1998, 29 (01) :4-11
[6]   Neurologic outcome in survivors of childhood arterial ischemic stroke and sinovenous thrombosis [J].
deVeber, GA ;
MacGregor, D ;
Curtis, R ;
Mayank, S .
JOURNAL OF CHILD NEUROLOGY, 2000, 15 (05) :316-324
[7]   Deaths from stroke in US children, 1979 to 1998 [J].
Fullerton, HJ ;
Chetkovich, DM ;
Wu, YW ;
Smith, WS ;
Johnston, SC .
NEUROLOGY, 2002, 59 (01) :34-39
[8]   Intra-arterial prourokinase for acute ischemic stroke - The PROACT II study: A randomized controlled trial [J].
Furlan, A ;
Higashida, R ;
Wechsler, L ;
Gent, M ;
Rowley, H ;
Kase, C ;
Pessin, M ;
Ahuja, A ;
Callahan, F ;
Clark, WM ;
Silver, F ;
Rivera, F .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (21) :2003-2011
[9]   Posterior circulation stroke in childhood - Risk factors and recurrence [J].
Ganesan, V ;
Chong, WK ;
Cox, TC ;
Chawda, SJ ;
Prengler, M ;
Kirkham, FJ .
NEUROLOGY, 2002, 59 (10) :1552-1556
[10]   Outcome after ischaemic stroke in childhood [J].
Ganesan, V ;
Hogan, A ;
Shack, N ;
Gordon, A ;
Isaacs, E ;
Kirkham, FJ .
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2000, 42 (07) :455-461