The prevalence of osteoporosis in patients with severe hip and knee osteoarthritis awaiting joint arthroplasty

被引:85
作者
Lingard, Elizabeth A. [1 ,5 ]
Mitchell, Sheryl Y. [1 ]
Francis, Roger M. [2 ,5 ]
Rawlings, David [3 ]
Peaston, Robert [4 ]
Birrell, Fraser N. [5 ]
McCaskie, Andrew W. [1 ,5 ]
机构
[1] Freeman Rd Hosp, Dept Orthopaed Surg, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
[2] Freeman Rd Hosp, Bone Clin, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
[3] Freeman Rd Hosp, Dept Med Phys, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
[4] Freeman Rd Hosp, Dept Biochem, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
[5] Univ Newcastle, Sch Med, Inst Cellular Med, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England
关键词
osteoporosis; osteoarthritis; hip; knee; bone mineral density; elderly; BONE-MINERAL DENSITY; ELDERLY-MEN; WOMEN; PRECISION; FRACTURES; ARTHRITIS; RISK;
D O I
10.1093/ageing/afp222
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objective: to determine the prevalence of osteoporosis among patients with osteoarthritis awaiting total knee arthroplasty or total hip arthroplasty aged between 65 and 80 years. Design: cross-sectional observational study. Setting: tertiary referral centre in Newcastle upon Tyne, UK. Subjects: patients with osteoarthritis awaiting total knee hip arthroplasty aged between 65 and 80 years. Methods: lumbar spine, bilateral femoral and forearm bone mineral density (BMD) measurements were obtained using dual-energy X-ray absorptiometry. Results: the cohort consisted of 199 patients with a mean age of 72 years (SD 4), and 113 (57%) were women. The overall rate of osteoporosis at any site was 23% (46/199) and a further 43% (85/199) of patients would have been classified as osteopaenic according to World Health Organization criteria. Osteoporosis was more commonly detected in the forearm (14%) than the lumbar spine (8.5%) and proximal femur of the index side (8.2%). Conclusions: in summary, a significant proportion of patients with end-stage OA have osteoporosis but this diagnosis may be missed unless BMD measurements are performed at sites distant from joints affected by OA.
引用
收藏
页码:234 / 239
页数:6
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