Cerebral blood flow and oxygenation during head-up tilt in patients with multiple system atrophy and healthy control subjects

被引：11

作者：

Asahina, Masato

Sato, Jiro

Tachibana, Masatoshi

Hattori, Takamichi

机构：

[1] Chiba Univ, Sch Med, Dept Neurol, Chuo Ku, Chiba 2608670, Japan

[2] Natl Chiba Med Ctr, Dept Anesthesia, Chuo Ku, Chiba 2608606, Japan

[3] Chiba Univ, Sch Med, Dept Otolaryngol, Chuo Ku, Chiba 2608670, Japan

来源：

PARKINSONISM & RELATED DISORDERS | 2006年 / 12卷 / 08期

关键词：

autonomic failure; cerebral autoregulation; cerebral blood flow; cerebral oxygenation; multiple system atrophy; orthostatic hypotension;

D O I：

10.1016/j.parkreldis.2006.05.002

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To assess cerebral hemodynamics in patients with multiple system atrophy (MSA), cerebral blood flow and oxygenation were evaluated in 7 MSA patients and 9 healthy controls during a head-up tilt test (HUT) by means of transcranial Doppler ultrasonography and near-infrared spectrophotometry. In the MSA patients examined, the perfusion pressure reduction during HUT was marked, but severe reduction in blood flow velocity was prevented because of a decrease in cerebrovascular resistance. The MSA patients showed no severe reduction in cerebral oxygenation during HUT. These findings indicate that our MSA patients exhibited a compensatory cerebral vasodilatation response to orthostatic hypotension. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：472 / 477

页数：6

共 26 条

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