Nuclear coupling: RNA processing reaches back to transcription

被引：42

作者：

Manley, JL ^{[1
]}

机构：

[1] Columbia Univ, Dept Biol Sci, New York, NY 10027 USA

来源：

NATURE STRUCTURAL BIOLOGY | 2002年 / 9卷 / 11期

关键词：

D O I：

10.1038/nsb1102-790

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Considerable evidence indicates that the processes involved in synthesizing mature messenger RNA in the eukaryotic nucleus are intimately coupled to one another. RNA polymerase II plays an important role in all of these events, participating in its primary function in transcription as well as in subsequent RNA processing. Unexpectedly, recent studies indicate that RNA processing factors can reciprocate, 'reaching back' in the pathway to influence transcription.

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页码：790 / 791

页数：2

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