COMPARATIVE STUDY OF ORAL ANTIDIABETIC THERAPY AND INSULIN THERAPY ON HEPATIC STEATOSIS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

被引：9

作者：

Hoza, Anica ^{[1
]}

Moldovan, Corina ^{[1
]}

Farcas, Dorina Maria ^{[1
]}

Pallag, Annamaria ^{[1
]}

Nemeth, Sebastian ^{[1
]}

Marc, Felicia ^{[1
]}

机构：

[1] Univ Oradea, Fac Med & Pharm, Oradea, Romania

来源：

FARMACIA | 2018年 / 66卷 / 04期

关键词：

type 2 diabetes mellitus; hepatic steatosis; insulin therapy oral antidiabetics; FATTY LIVER-DISEASE; NONALCOHOLIC STEATOHEPATITIS; UNITED-STATES; PREVALENCE; LIPOTOXICITY; POPULATION; NUTRITION; MODEL;

D O I：

10.31925/farmacia.2018.4.14

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In type 2 diabetes mellitus (DM) patients, hepatic steatosis is present in a much higher proportion than in healthy people. In this study, we have evaluated the presence of steatosis in patients with type 2 DM, and whether this may be correlated with the type of treatment that patients are using, either with oral antidiabetics (OAD), or with insulin therapy +/- OAD. In the same time, steatosis has been correlated with nutritional status, metabolic control, and lipidic profile. The results showed that patients treated with insulin, exhibited hepatic steatosis in a statistically significant lower percent than patients treated with OAD. This finding is maintained after the correlation with weight status or metabolic control.

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页码：652 / 657

页数：6

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