Metabolites from Clonostachys Fungi and Their Biological Activities

被引：31
作者：
Han, Peipei [1 ]
Zhang, Xuping [1 ]
Xu, Dan [1 ]
Zhang, Bowen [1 ]
Lai, Daowan [1 ]
Zhou, Ligang [1 ]
机构：
[1] China Agr Univ, Coll Plant Protect, Dept Plant Pathol, Beijing 100193, Peoples R China
来源：
JOURNAL OF FUNGI | 2020年 / 6卷 / 04期
基金：
国家重点研发计划;
关键词：
secondary metabolites; Clonostachys fungi; Bionectria; Gliocladium; Nectria; structural diversity; biological activities; ENDOPHYTIC FUNGUS; NECTRIA-HAEMATOCOCCA; CHITINASE INHIBITOR; GLIOCLADIUM-ROSEUM; BIONECTRIA SP; SECONDARY METABOLITES; BIOACTIVE METABOLITES; ACID-DERIVATIVES; ALPHA-PYRONES; POLYKETIDE;
D O I：
10.3390/jof6040229
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Clonostachys (teleomorph: Bionectria) fungi are well known to produce a variety of secondary metabolites with various biological activities to show their pharmaceutical and agrochemical applications. Up to now, at least 229 secondary metabolites, mainly including 84 nitrogen-containing metabolites, 85 polyketides, 40 terpenoids, and 20 other metabolites, have been reported. Many of these compounds exhibit biological activities, such as cytotoxic, antimicrobial, antileishmanial, antimalarial activities. This mini-review aims to summarize the diversity of the secondary metabolites as well as their occurrences in Clonostachys fungi and biological activities.
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页码：1 / 30
页数：31
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