JADE: a distributed Java']Java application for deleterious genomic mutation (DGM) estimation

被引：1

作者：

Li, J. -L.

Li, M. -X.

Guo, Y. -F.

Deng, H. -Y.

Deng, H. -W. ^{[1
]}

机构：

[1] Hunan Normal Univ, Lab Mol & Stat Genet, Coll Life Sci, Changsha 410081, Peoples R China

[2] Seattle Biomed Res Inst, Seattle, WA 98109 USA

[3] Shanghai Ctr Bioinformat Technol, Shanghai 200235, Peoples R China

[4] Univ Missouri, Sch Med, Dept Orthoped Surg, Kansas City, MO 64108 USA

[5] Univ Missouri, Sch Med, Dept Basic Med Sci, Kansas City, MO 64108 USA

[6] Creighton Univ, Med Ctr, Osteoporosis Res Ctr, Omaha, NE 68131 USA

来源：

BIOINFORMATICS | 2006年 / 22卷 / 15期

基金：

美国国家卫生研究院; 中国国家自然科学基金;

关键词：

NATURAL-POPULATIONS; PARAMETERS;

D O I：

10.1093/bioinformatics/btl278

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The characterization of deleterious genomic mutation (DGM) is of central significance for evolutionary biology and genetic studies. Fitness moment method has been developed to efficiently characterize DGM from natural population directly. In order to enable researchers to employ this method for theoretical and empirical research on characterizing DGM, we here present a distributed Java Application for DGM Estimation (JADE).

引用

页码：1926 / 1927

页数：2

共 9 条

[1] THE VIABILITY OF NEAR-NORMAL IRRADIATED CHROMOSOMES [J].