共 61 条
Super-Resolution Microscopy: A Virus' Eye View of the Cell
被引:24
作者:

Grove, Joe
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机构:
UCL, Inst Immun & Transplantat, London NW3 2PF, England UCL, Inst Immun & Transplantat, London NW3 2PF, England
机构:
[1] UCL, Inst Immun & Transplantat, London NW3 2PF, England
来源:
VIRUSES-BASEL
|
2014年
/
6卷
/
03期
关键词:
microscopy;
super-resolution;
PALM;
STORM;
dSTORM;
tetraspanin;
virus assembly;
virus entry;
TETRASPANIN-ENRICHED MICRODOMAINS;
PHOTOACTIVATED LOCALIZATION MICROSCOPY;
PAIR CORRELATION-ANALYSIS;
PLASMA-MEMBRANE;
ASSEMBLY SITES;
FLUORESCENCE MICROSCOPY;
RESOLUTION LIMIT;
CD81;
HIV-1;
MOLECULES;
D O I:
10.3390/v6031365
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
It is difficult to observe the molecular choreography between viruses and host cell components, as they exist on a spatial scale beyond the reach of conventional microscopy. However, novel super-resolution microscopy techniques have cast aside technical limitations to reveal a nanoscale view of virus replication and cell biology. This article provides an introduction to super-resolution imaging; in particular, localisation microscopy, and explores the application of such technologies to the study of viruses and tetraspanins, the topic of this special issue.
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收藏
页码:1365 / 1378
页数:14
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