Effect of difructose anhydride III on calcium absorption in humans

被引：42
作者：
Shigematsu, N
Okuhara, Y
Shiomi, T
Tomita, F
Hara, H
机构：
[1] FANCL Co Ltd, Food Res Div, Cent Res Lab, Totsuka Ku, Yokohama, Kanagawa 2440806, Japan
[2] Hokkaido Univ, Grad Sch Agr, Div Appl Biosci, Sapporo, Hokkaido 0608589, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2004年 / 68卷 / 05期
关键词：
difuructose anhydride III; calcium; deoxypyridinoline; urine; human;
D O I：
10.1271/bbb.68.1011
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The effects of difructose anhydride III (DFAIII) on stimulating calcium absorption was investigated in humans. We studied changes in the time-course of characteristics urinary calcium excretion in 12 healthy men given 0.3, 1.0 or 3.0 g of DFAIII and 300 mg of calcium as calcium carbonate. In addition, urinary excretion and urine concentrations of creatinine and deoxypyridinoline were determined. Urine calcium excretion every 2 hours after the intake were higher over than that of the control subjects. The total amount of urinary calcium excretion for 10 hours was significantly greates in the subjects given 1.0 g or 3.0 g of DFAIII than that of the control subjects. However, there were no differences in the urine concentrations of creatinine and deoxypyridinoline between the subjects given DFAIII and the control subjects. These findings suggests that low dose of DFAIII had a stimulating effect on calcium absorption in humans.
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页码：1011 / 1016
页数：6
相关论文
共 20 条
[1]   Effect of soluble or partly soluble dietary fibres supplementation on absorption and balance of calcium, magnesium, iron and zinc in healthy young men [J].
Coudray, C ;
Bellanger, J ;
CastigliaDelavaud, C ;
Remesy, C ;
Vermorel, M ;
Rayssignuier, Y .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 1997, 51 (06) :375-380
[2]   Zinc and calcium apparent absorption from an infant cereal: A stable isotope study in healthy infants [J].
Davidsson, L ;
Mackenzie, J ;
Kastenmayer, P ;
Aggett, PJ ;
Hurrell, RF .
BRITISH JOURNAL OF NUTRITION, 1996, 75 (02) :291-300
[3]  
Fujita T., 1996, J BONE MINER METAB, V14, P31, DOI [10.1007/BF01771671, DOI 10.1007/BF01771671]
[4]  
Heaney R.P., 1994, J BONE MINER METAB, V12, P77, DOI [10.1007/BF02383413, DOI 10.1007/BF02383413]
[5]  
Hosono A, 1997, JJS MG RES, V16, P87
[6]   Absorptive activity of calcium in the isolated cecal epithelium adaptively increased by 2 week's feeding of difructose anhydride III in rats [J].
Mineo, H ;
Amano, M ;
Chiji, H ;
Shigematsu, N ;
Tomita, F ;
Hara, H .
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2003, 67 (08) :1847-1851
[7]   Melibiose, difructose anhydride III and difructose anhydride IV enhance net calcium absorption in rat small and large intestinal epithelium by increasing the passage of tight junctions in vitro [J].
Mineo, H ;
Hara, H ;
Shigematsu, N ;
Okuhara, Y ;
Tomita, F .
JOURNAL OF NUTRITION, 2002, 132 (11) :3394-3399
[8]   Supplemental feeding of difructose anhydride III restores calcium absorption impaired by ovariectomy in rats [J].
Mitamura, R ;
Hara, H ;
Aoyama, Y ;
Chiji, H .
JOURNAL OF NUTRITION, 2002, 132 (11) :3387-3393
[9]  
NORDIN BEC, 1990, ILSI HUMAN NUTR REV, P137
[10]  
NORDIN BEC, 1990, ILSI HUMAN NUTR REV, P447
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