Synthesis and antibacterial activity of novel arylbis(indol-3-yl)methane derivatives

被引:6
作者
Panov, Alexey A. [1 ]
Lavrenov, Sergey N. [1 ]
Mirchink, Elena P. [1 ]
Isakova, Elena B. [1 ]
Korolev, Alexander M. [1 ]
Trenin, Alexey S. [1 ]
机构
[1] Gause Inst New Antibiot, 11 B Pirogovskaya St, Moscow 119021, Russia
基金
俄罗斯科学基金会;
关键词
SALTS;
D O I
10.1038/s41429-020-00389-9
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
A series of new compounds-arylbis(indol-3-yl)methylium derivatives-were synthesized and their antimicrobial activity was evaluated. All the compounds turned out to be highly active, with MIC depending on their structure and the length of N-alkyl residues. The parent triarylmethane compounds possess weaker activity.
引用
收藏
页码:219 / 224
页数:6
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